07-617
Anti-mGluR1 Antibody
Upstate®, from rabbit
Synonym(s):
Anti-GPRC1A, Anti-MGLU1, Anti-MGLUR1, Anti-PPP1R85, Anti-SCA44, Anti-SCAR13
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All Photos(2)
About This Item
UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Recommended Products
biological source
rabbit
Quality Level
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
polyclonal
species reactivity
rat
manufacturer/tradename
Upstate®
technique(s)
western blot: suitable
isotype
IgG
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
human ... GRM1(2911)
Specificity
Predicted to cross-react with human and mouse based on sequence homology
mGluR1
Immunogen
peptide corresponding to amino acids 1180-1199 (C-PNVTYASVILRDYKQSSSTL) of rat mGluR1
Application
Anti-mGluR1 Antibody detects level of mGluR1 & has been published & validated for use in WB.
Research Category
Neuroscience
Neuroscience
Research Sub Category
Neurotransmitters & Receptors
Neurodegenerative Diseases
Neurotransmitters & Receptors
Neurodegenerative Diseases
Quality
routinely evaluated by immunoblot on mGluR1 in rat brain microsomal preparation
Target description
142kDa
Physical form
0.1M Tris-glycine, pH 7.4, 0.15M NaCl, and 0.05% sodium azide.
Format: Purified
Protein A purified
Storage and Stability
Stable for 1 year at 2-8°C from date of receipt.
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
WGK
WGK 1
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Reduced metabotropic glutamate receptor 5 density in major depression determined by [(11)C]ABP688 PET and postmortem study.
Deschwanden, A; Karolewicz, B; Feyissa, AM; Treyer, V; Ametamey, SM; Johayem, A; Burger et al.
The American Journal of Psychiatry null
D D Wright et al.
The Journal of comparative neurology, 364(4), 729-745 (1996-01-22)
We demonstrate that the metabotropic glutamate receptor mGluR1 alpha is enriched in two interneuron cell populations in the dorsal division of the cochlear nucleus. Electron microscopic analysis confirms that mGluR1 alpha immunoreactivity is concentrated in the dendritic spines of cartwheel
Tianyu Bai et al.
Cellular and molecular neurobiology (2022-07-08)
The underlying mechanisms of opioid-induced hyperalgesia (OIH) remain unclear. Herein, we found that the protein expression of metabotropic glutamate receptor 1 (mGluR1) was significantly increased in the right but not in the left laterocapsular division of central nucleus of the
Swarna Pandian et al.
eNeuro, 7(6) (2020-11-25)
Myosin Va (MyoVa) is a plus-end filamentous-actin motor protein that is highly and broadly expressed in the vertebrate body, including in the nervous system. In excitatory neurons, MyoVa transports cargo toward the tip of the dendritic spine, where the postsynaptic
Glutamate and the glutamate receptor system: a target for drug action.
Bleich, Stefan, et al.
International Journal of Geriatric Psychiatry, 18, S33-S40 (2003)
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