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860060P

Avanti

Ganglioside GD3 (Bovine Milk)

Avanti Research™ - A Croda Brand

Synonym(s):

110954

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About This Item

CAS Number:
1246353-20-7
UNSPSC Code:
12352211
NACRES:
NA.25

description

GD3 Ganglioside (Milk, Bovine-Ammonium Salt)

Assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 1 mg (860060P-1mg)
pkg of 1 × 5 mg (860060P-5mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand

lipid type

lipid extracts
sphingolipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@](/C=C/CCCCCCCCCCCCC)(O)[C@@]([H])(NC(CCCCCCCCCCCCCCCCC)=O)CO[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@@H]2O[C@H](CO)[C@@H]([C@H](O[C@@]3(C([O-])=O)O[C@@H]([C@H](O)[C@H](O)CO[C@@]4(C([O-])=O)O[C@@H]([C@H](O)[C@H](O)CO)[C@@](NC(C)=O)([H])[C@@H](O)C4)[C@@](NC(

General description

Gangliosides are glycosphingolipids containing a hydrophobic ceramide and hydrophilic oligosaccharide chain. They are found in various tissues and fluids in vertebrates, especially in human brain and bovine milk. The most common gangliosides in milk are 2NeuAc−2Hex−Cer (GD3) and NeuAc−2Hex−Cer (GM3).

Application

Ganglioside GD3 (Bovine Milk) is suitable as a lipid standard in Fourier-transform ion cyclotron resonance (FTICR) mass spectrometric analysis and liquid chromatography−mass spectrometry (LC-MS/MS) data analysis.

Biochem/physiol Actions

Gangliosides are involved in neuronal development, neuropathologic processes, receptor interactions with protein hormones, interferon, fibronectin and toxins from bacteria, They are also essential for the development of intestinal immunity by producing intestinal IgA and cytokine.

Packaging

5 mL Amber Glass Screw Cap Vial (860060P-1mg)
5 mL Amber Glass Screw Cap Vial (860060P-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

also commonly purchased with this product

Product No.
Description
Pricing

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

No data available

Flash Point(C)

No data available

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Disialoganglioside-GD2 from bovine brain ~95%, lyophilized powder, semisynthetic

Sigma-Aldrich

G0776

Disialoganglioside-GD2 from bovine brain

Variation of the ganglioside compositions of human milk, cow?s milk and infant formulas
Pan X L, et al.
Early Human Development, 57(1), 25-31 (2000)
The role of dietary gangliosides on immunity and the prevention of infection
Rueda R
The British Journal of Nutrition, 98(S1), S68-S73 (2007)
Intact glycosphingolipidomic analysis of the cell membrane during differentiation yields extensive glycan and lipid changes
Wong M, et al.
Scientific reports, 8(1), 10993-10993 (2018)
Rapid profiling of bovine and human milk gangliosides by matrix-assisted laser desorption/ionization Fourier transform ion cyclotron resonance mass spectrometry
Lee H, et al.
International Journal of Mass Spectrometry, 305(2-3), 138-150 (2011)
Combination of ESI and MALDI mass spectrometry for qualitative, semi-quantitative and in situ analysis of gangliosides in brain
Zhang Y, et al.
Scientific Reports, 6, 25289-25289 (2016)
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