Drug metabolism and disposition: the biological fate of chemicals, 18(4), 447-452 (1990-07-01)
The single-dose toxicokinetics of monomethylamine has been characterized in the rat by HPLC assay of serial blood samples. Biphasic first-order elimination was observed following an iv bolus dose of 19 mumol/kg with a terminal half-life of 19.1 +/- 1.3 min
Following short-term local applications of high doses of N-methyl-N-nitrozourea and 7,2-dimethylbenz(a)antracen, the intercellular adhesion in the distal colon epithelium of ice retains increased at least for a month. The magnitude of this shift and its duration ops both with moving
The in vivo nitrosation capacity of third-instar larvae of Drosophila melanogaster was assessed using the wing somatic mutation and recombination test (SMART). Larvate derived from two different crosses, the standard cross (ST) and the high bioactivation cross (HB) both involving
American journal of physiology. Regulatory, integrative and comparative physiology, 297(2), R313-R322 (2009-05-22)
Gulf toadfish (Opsanus beta) use a unique pulsatile urea excretion mechanism that allows urea to be voided in large pulses via the periodic insertion or activation of a branchial urea transporter. The precise cellular and subcellular location of the facilitated
Physical chemistry chemical physics : PCCP, 14(38), 13273-13283 (2012-08-25)
The phenomenon of solid-state proton migration within molecular complexes containing short hydrogen bonds is investigated in two dimethylurea-oxalic acid complexes. Extensive characterisation by both X-ray and neutron diffraction shows that proton migration along the hydrogen bond can be induced in
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.