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96895

Sigma-Aldrich

Z-Lys-ONp hydrochloride

≥98.0% (AT)

Synonym(s):

Nα-Z-L-lysine 4-nitrophenyl ester hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C20H23N3O6 · HCl
CAS Number:
2179-15-9
Molecular Weight:
437.87
Beilstein:
7191805
EC Number:
218-546-5
MDL number:
MFCD00039055
UNSPSC Code:
12352200
PubChem Substance ID:
57653793
NACRES:
NA.22

Assay

≥98.0% (AT)

form

powder

optical activity

[α]20/D −24±1°, c = 1% in DMF

mp

146-152 °C

application(s)

peptide synthesis

storage temp.

−20°C

SMILES string

Cl.NCCCC[C@H](NC(=O)OCc1ccccc1)C(=O)Oc2ccc(cc2)[N+]([O-])=O

InChI

1S/C20H23N3O6.ClH/c21-13-5-4-8-18(22-20(25)28-14-15-6-2-1-3-7-15)19(24)29-17-11-9-16(10-12-17)23(26)27;/h1-3,6-7,9-12,18H,4-5,8,13-14,21H2,(H,22,25);1H/t18-;/m0./s1

InChI key

JFZLPXVXTZKFDV-FERBBOLQSA-N

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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R B Aĭsina et al.
Bioorganicheskaia khimiia, 20(2), 182-189 (1994-02-01)
The effect of L-lysine on some reactions catalysed by plasmin and the plasmin-streptokinase activator complex has been studied. The constants for competitive inhibition by L-lysine of the benzyloxycarbonyl-L-lysine p-nitrophenyl ester hydrolysis by the activator (Ki 116 mM), of the plasminogen
P Ascenzi et al.
Biochimica et biophysica acta, 871(3), 319-323 (1986-06-23)
Values of steady-state and pre-steady-state parameters for the bovine alpha-thrombin-catalyzed hydrolysis of ZArgONp and ZLysONp have been determined between pH 2.5 and 8 (I = 0.1 M) at 21 +/- 0.5 degree C. Kinetic properties of bovine alpha-thrombin have been
Srinath Kasturi Rangan et al.
Biochemistry, 42(48), 14328-14334 (2003-12-03)
Deposition of beta-amyloid (Abeta) is considered an important early event in the pathogenesis of Alzheimer's disease (AD). Clearance of Abeta thus represents a potential therapeutic approach. Antibody-mediated clearance of Abeta by vaccination inhibited and cleared Abeta deposition in animal models;
P Ascenzi et al.
Biochimica et biophysica acta, 871(2), 225-228 (1986-06-05)
Values of steady-state and pre-steady-state parameters for the hydrolysis of ZArgONp and ZLysONp catalysed by ancrod, the coagulating serine proteinase from the Malayan pit viper (Agkistrodon rhodostoma) venom, have been determined, between pH 2.5 and 8 (I = 0.1 M)
P Ascenzi et al.
Biochimica et biophysica acta, 829(3), 415-423 (1985-07-01)
Kinetics for the hydrolysis of p-nitrophenyl esters of N-alpha-carbobenzoxy-L-amino acids catalyzed by Ancrod were determined between pH 5 and 10 (I = 0.1 M) at 21 +/- 0.5 degrees C; the results are consistent with the minimum three-step mechanism: (formula:
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