708496
Acetyl chloride solution
1 M in methylene chloride
Sign Into View Organizational & Contract Pricing
All Photos(1)
About This Item
Empirical Formula (Hill Notation):
C2H3ClO
CAS Number:
Molecular Weight:
78.50
MDL number:
UNSPSC Code:
12352101
PubChem Substance ID:
NACRES:
NA.22
Recommended Products
form
liquid
concentration
1 M in methylene chloride
refractive index
n20/D 1.423
density
1.294 g/mL at 25 °C
SMILES string
CC(Cl)=O
InChI
1S/C2H3ClO/c1-2(3)4/h1H3
InChI key
WETWJCDKMRHUPV-UHFFFAOYSA-N
Application
Acetyl chloride (AcCl) can be used as:
- An acylating reagent to prepare useful key intermediates in organic synthesis.
- A reagent to convert oxathioacetals and dithioacetals into corresponding carbonyl compounds in the presence of sodium nitrite.
- An activating or acylating reagent in solid-phase organic synthesis.
- A reagent to prepare various alkyl and aryl tetrahydropyranyl ethers from corresponding alcohols.
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Carc. 2 - Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1B - STOT SE 3
Target Organs
Central nervous system
WGK
WGK 2
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
New phenylfluorenyl based linkers for solid phase synthesis
Bleicher KH, et al.
Tetrahedron Letters, 41(47), 9037-9042 (2000)
Selective synthesis of spirooxindoles via a two-step reaction of N-phenacylpyridinium bromide, 1, 3-indanedione and N-alkylisations
Sun J, et al.
Organic & Biomolecular Chemistry, 17(16), 3978-3983 (2019)
Solid phase synthesis of styrylquinazolinones
Theoclitou M-E, et al.
Tetrahedron Letters, 41(13), 2051-2054 (2000)
A highly efficient procedure for regeneration of carbonyl groups from their corresponding oxathioacetals and dithioacetals using sodium nitrite and acetyl chloride in dichloromethane
Khan AT, et al.
Synlett, 2003(03), 0377-0381 (2003)
Acetyl chloride-mediated mild and chemoselective attachment and removal of tetrahydropyranyl (THP) group
Yeom C-E, et al.
Bulletin of the Korean Chemical Society,, 28(1), 103-107 (2007)
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service