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670049

Sigma-Aldrich

O-[2-(Biotinyl-amino)ethyl]-O′-[3-(N-succinimidyloxy)-3-oxopropyl]polyethylene glycol

Mp 3,000

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About This Item

CAS Number:
948595-10-6
UNSPSC Code:
12352200
NACRES:
NA.22

mol wt

Mp 3,000

Ω-end

NHS ester

α-end

biotin

storage temp.

−20°C

Application

O-[2-(Biotinyl-amino)ethyl]-O′-[3-(N-succinimidyloxy)-3-oxopropyl]polyethylene glycol may be used to functionalize far red emitting persistent luminescence nanoparticles (PLNP).

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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In vitro targeting of avidin-expressing glioma cells with biotinylated persistent luminescence nanoparticles.
Maldiney T, et al.
Bioconjugate Chemistry, 23(3), 472-478 (2012)

Articles

Degradable Poly(ethylene glycol) Hydrogels for 2D and 3D Cell Culture

Progress in biotechnology fields such as tissue engineering and drug delivery is accompanied by an increasing demand for diverse functional biomaterials. One class of biomaterials that has been the subject of intense research interest is hydrogels, because they closely mimic the natural environment of cells, both chemically and physically and therefore can be used as support to grow cells. This article specifically discusses poly(ethylene glycol) (PEG) hydrogels, which are good for biological applications because they do not generally elicit an immune response. PEGs offer a readily available, easy to modify polymer for widespread use in hydrogel fabrication, including 2D and 3D scaffold for tissue culture. The degradable linkages also enable a variety of applications for release of therapeutic agents.

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