542903

3-Chloro-4-fluoroiodobenzene

98%

• Linear Formula: ClC₆H₃(F)I
• CAS Number: 156150-67-3
• Molecular Weight: 256.44
• MDL number: MFCD00042210
• UNSPSC Code: 12352100
• PubChem Substance ID: 24878644
• NACRES: NA.22

Properties

• Assay: 98%
• refractive index: n20/D 1.604 (lit.)
• bp: 94-95 °C/15 mmHg (lit.)
• density: 2.008 g/mL at 25 °C (lit.)
• SMILES string: Fc1ccc(I)cc1Cl
• InChI: 1S/C6H3ClFI/c7-5-3-4(9)1-2-6(5)8/h1-3H
• InChI key: OMASDGWBVAVFQZ-UHFFFAOYSA-N

Description

General description

3-Chloro-4-fluoroiodobenzene, also known as 2-chloro-1-fluoro-4-iodobenzene [IUPAC name], is a polyhalobenzene. It participates in the synthesis of 3-carboxythiophene analogs.

Application

3-Chloro-4-fluoroiodobenzene may be used in the preparation of 2-chloro-1-(3,5-dimethoxyphenoxy)-4-iodobenzene by reacting with 3,5-dimethoxyphenol in the presence of cesium carbonate.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H315,H319,H335
• Precautionary Statements: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 3
• Flash Point(F): 230.0 °F - closed cup
• Flash Point(C): 110 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves