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47632

Sigma-Aldrich

Fmoc-Arg(Mtr)-OH

≥98.0% (TLC)

Synonym(s):

Nα-Fmoc-Nω-(4-methoxy-2,3,6-trimethylbenzenesulfonyl)-L-arginine, Nα-Fmoc-Nω-MTR-L-arginine

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About This Item

Empirical Formula (Hill Notation):
C31H36N4O7S
CAS Number:
Molecular Weight:
608.71
Beilstein:
5206491
MDL number:
UNSPSC Code:
12352200
eCl@ss:
32160406
PubChem Substance ID:

Assay

≥98.0% (TLC)

application(s)

peptide synthesis

functional group

Fmoc

storage temp.

−20°C

SMILES string

COc1cc(C)c(c(C)c1C)S(=O)(=O)NC(=N)NCCC[C@H](NC(=O)OCC2c3ccccc3-c4ccccc24)C(O)=O

InChI

1S/C31H36N4O7S/c1-18-16-27(41-4)19(2)20(3)28(18)43(39,40)35-30(32)33-15-9-14-26(29(36)37)34-31(38)42-17-25-23-12-7-5-10-21(23)22-11-6-8-13-24(22)25/h5-8,10-13,16,25-26H,9,14-15,17H2,1-4H3,(H,34,38)(H,36,37)(H3,32,33,35)/t26-/m0/s1

InChI key

LKGHIEITYHYVED-SANMLTNESA-N

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Other Notes

Protected arginine derivative used in solid phase peptide synthesis. The MTR-guanidine protection of arg is more acid-sensitive than the tosyl group

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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M P Williamson et al.
European journal of biochemistry, 158(3), 527-536 (1986-08-01)
The peptide alpha Ahx-Met-Ala-Asp-Pro-Asn-Arg-Phe-Arg-Gly-Lys-Asp-Leu-Pro-Val-Leu- Asp-Gln-Leu-Thr-Asp-Pro-Pro-alpha Ahx (epsilon Ahx = 6-aminohexanoyl), the antigenic sequence 11-32 from Herpes simplex virus glycoprotein D-1, has been synthesised. Its 1H-NMR spectrum has been assigned by a combination of two-dimensional techniques in H2O and 2H2O. Its
E. Atherton et al.
Journal of the Chemical Society. Perkin Transactions 1, 2065-2065 (1985)
M. Fujino et al.
Chemical & Pharmaceutical Bulletin, 29, 2825-2825 (1981)

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