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Sigma-Aldrich

Novatach™ LVM GRGDSP

GRGDSP-peptide coupled high M sodium alginate, mannuronate acid content ≥50 %

Synonym(s):

Peptide coupled alginate

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About This Item

UNSPSC Code:
12352202
NACRES:
NA.25

Quality Level

100

form

powder

composition

mannuronate acid content, ≥50%

impurities

≤100 EU/g Endotoxins

pH

5.5-8.5 (20 °C, 1% in water)

General description

Modified sodium alginate, grafted with RGD peptide sequences, Novatach Peptide-coupled UP Alginates are designed to facilitate and promote interaction between cells and alginate-based scaffolds and matrices. They are useful when cell-to-matrix interactions are beneficial. The GRGDSP peptide sequence is a common example of such adhesion ligand used for MSC stem cells. The peptide alginate is available with four different alginate backbones giving flexibility to match hydrogel properties in your application.

Application

Novatach Peptide-coupled UP Alginates: initiator for biological interactions between alginate hydrogels and cells, encapsulation of living cells and therapeutic proteins for cell therapy medications, 3D bioprinting, foams and cell tissue scaffolds, hydrogels, advanced drug delivery, etc.

Legal Information

Product of Dupont Nutrition USA, Inc.
NOVATACH is a trademark of Dupont Nutrition USA, Inc.

Disclaimer

NOT FOR USE IN HUMANS

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Articles

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Engineered ECMs enhance immune therapy in cancer treatment by supporting cells and tissues and modulating immune response. They improve immune cell maturation, expansion, and regulation through biomaterial manipulation, acting as frameworks or carriers for enhanced tumor immunotherapy.

Rational Design of ECMs Toward Cancer Immunotherapy

Engineered ECMs enhance immune therapy in cancer treatment by supporting cells and tissues and modulating immune response. They improve immune cell maturation, expansion, and regulation through biomaterial manipulation, acting as frameworks or carriers for enhanced tumor immunotherapy.

Rational Design of ECMs Toward Cancer Immunotherapy

Engineered ECMs enhance immune therapy in cancer treatment by supporting cells and tissues and modulating immune response. They improve immune cell maturation, expansion, and regulation through biomaterial manipulation, acting as frameworks or carriers for enhanced tumor immunotherapy.

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