392170

Methyl 3,4-O-isopropylidene-L-threonate

97%

• Synonym(s): (αR,4S)-2,2-Dimethyl-α-hydroxy-1,3-dioxolane-4-acetic acid methyl ester, 3,4-O-Isopropylidene-L-threonic acid methyl ester
• Empirical Formula (Hill Notation): C₈H₁₄O₅
• CAS Number: 92973-40-5
• Molecular Weight: 190.19
• Beilstein: 7862
• UNSPSC Code: 12352201
• PubChem Substance ID: 24864430
• NACRES: NA.22

Properties

• Assay: 97%
• form: liquid
• optical activity: [α]20/D +18.5°, c = 2 in acetone
• refractive index: n20/D 1.446 (lit.)
• bp: 125 °C/12 mmHg (lit.)
• density: 1.175 g/mL at 25 °C (lit.)
• SMILES string: COC(=O)[C@H](O)[C@@H]1COC(C)(C)O1
• InChI: 1S/C8H14O5/c1-8(2)12-4-5(13-8)6(9)7(10)11-3/h5-6,9H,4H2,1-3H3/t5-,6+/m0/s1
• InChI key: JSFASCPVVJBLRD-NTSWFWBYSA-N

Description

Application

Used to prepare a dihydrofuran substrate in the total synthesis of (-)-echinosporin.

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 3
• Flash Point(F): 210.2 °F - closed cup
• Flash Point(C): 99 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves