In this work pellets containing chitosan for colonic drug delivery were developed. The influence of the polysaccharide in the pellets was evaluated by swelling, drug dissolution and intestinal permeation studies. Drug-loaded pellets containing chitosan as swellable polymer were coated with
International journal of pediatric otorhinolaryngology, 77(1), 113-116 (2012-11-08)
The purpose of this prospective study was to determine the effectiveness of polyurethane foam (PUF) and polyvinyl acetate (PA) as packing materials for reducing post-conchotomy bleeding, pain, and headaches. This study was a prospective, randomized and single-blinded controlled study. Fifty-two
American journal of rhinology & allergy, 26(5), e147-e149 (2012-11-22)
This study investigated the efficacy of glove finger-coated polyvinyl acetate (PA) pack on hemostasis, pain levels, and wound healing after endoscopic sinus surgery (ESS). A prospective, randomized, double-blinded controlled study was performed in 30 patients who underwent bilateral ESS for
Pharmaceutical development and technology, 18(2), 481-489 (2012-09-25)
Differential scanning calorimetry and Fourier transform infrared spectroscopy were applied as screening analytical methods to assess the solid-state compatibility of indapamide (4-chloro-N-(2-methyl-2,3-dihydroindol-1-yl)-3-sulfamoyl-benzamide) with several polymers aimed for development of 24 h sustained release solid-dosage formulation. After the initial research phase which
International journal of pharmaceutics, 409(1-2), 9-18 (2011-02-22)
κ-Carrageenan is a novel pelletisation aid with high formulation robustness and quick disintegration leading to fast drug release unlike the matrix-like release from non-disintegrating microcrystalline cellulose pellets. Compression of pellets into tablets is cost effective. The feasibility of formulating multiparticulate
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