232505
1,2-Dihydroxynaphthalene
technical grade
Synonym(s):
1,2-Naphthalenediol
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About This Item
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grade
technical grade
mp
101-103 °C (lit.)
SMILES string
Oc1ccc2ccccc2c1O
InChI
1S/C10H8O2/c11-9-6-5-7-3-1-2-4-8(7)10(9)12/h1-6,11-12H
InChI key
NXPPAOGUKPJVDI-UHFFFAOYSA-N
General description
1,2-Dihydroxynaphthalene is the most sensitive biomarker for an internal exposure to naphthalene in humans.
Application
1,2-Dihydroxynaphthalene was used as substrate to investigate the rate of oxygen consumption by washed cell suspensions of Corynebacterium sp. strain C125 grown on o-xylene, tetralin or succinate.
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Target Organs
Respiratory system
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
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Naphthalene is considered by the US Environmental Protection Agency to be a carcinogenic compound based on inhalation studies in rats. The primary metabolite of naphthalene is naphthalene 1,2-arene oxide. This unstable intermediate can lead to formation of 1-naphthol and naphthalene-1,2-dihydrodiol.
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 102, 440-445 (2020-11-02)
The aim was to develop a reverse transcription loop-mediated isothermal amplification (RT-LAMP) assay for the detection of hepatitis C virus (HCV) in a single closed tube. Plasma samples were collected from 200 HCV-infected patients. HCV-RNA was detected by one-step RT-LAMP
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