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130435

Sigma-Aldrich

4-Dimethylamino-2-methylazobenzene

Synonym(s):

N,N-Dimethyl-4-phenylazo-m-toluidine

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About This Item

Linear Formula:
C6H5N=NC6H3(CH3)N(CH3)2
CAS Number:
54-88-6
Molecular Weight:
239.32
EC Number:
200-217-2
MDL number:
MFCD00008306
UNSPSC Code:
12171500
PubChem Substance ID:
24847962
NACRES:
NA.47

Quality Level

100

mp

67-69 °C (lit.)

SMILES string

CN(C)c1ccc(\N=N\c2ccccc2)c(C)c1

InChI

1S/C15H17N3/c1-12-11-14(18(2)3)9-10-15(12)17-16-13-7-5-4-6-8-13/h4-11H,1-3H3/b17-16+

InChI key

QXTOLYZIJUDOIT-WUKNDPDISA-N

Pictograms

Health hazardExclamation mark
GHS08,GHS07

Signal Word

Warning

Hazard Statements

H302,H351,H413

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 4 - Carc. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
STBD1691V
8601TJ
12208HS

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R Daoust
Chemico-biological interactions, 48(2), 221-235 (1984-02-01)
In order to obtain a more precise definition of the conditions under which 2-methyl-4-dimethylaminoazobenzene (2-Me-DAB) and liver cell proliferation play a role in the initiation of hepatocarcinogenesis, the toxicity of 2-Me-DAB for normal and partially hepatectomized rats was investigated. Continuous
G Yeoh et al.
European journal of cancer & clinical oncology, 18(11), 1163-1170 (1982-11-01)
The hepatocarcinogen 3'-methyl-4-dimethyl-aminoazobenzene (MDAB) suppresses the accumulation of tyrosine aminotransferase in cultured foetal hepatocytes. Experiments involving liver derived from foetuses of various ages reveals that a response is only obtained with rats older than 16-day gestation. It has been proposed
S Yanagi et al.
Journal of the National Cancer Institute, 73(4), 887-894 (1984-10-01)
A probably promoter-specific decrease of L-type pyruvate kinase (L-PK) in Wistar rat liver is described. The possibility of utilizing the decrease in L-PK activity for screening of hepatic promoters is discussed. A significantly decreased level of activity of L-PK was
Early events during liver carcinogenesis involving two carcinogen:protein complexes.
G R Blackburn et al.
Cancer research, 41(10), 4039-4049 (1981-10-01)
A R Samuels et al.
Biochimica et biophysica acta, 759(1-2), 23-31 (1983-08-23)
Following intravenous administration to rats of the azo dye hepatocarcinogen 3'-methyl-N,N-dimethyl-4-aminoazo-[14C]benzene, 60-70% of the injected dose was recovered in bile in 2 h. Approximately 10% of bile radioactivity was trichloroacetic acid-precipitable, not extracted by n-butanol and non-dialyzable. Sodium dodecyl sulfate-polyacrylamide
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