3-Bromothiophene can be used as a reactant to synthesize:
3,3-Bithiophene via borylation followed by Suzuki coupling.[1]
3-Alkylthiophenes by NiDPPP++ catalyzed cross-coupling with Grignard reagents.[2]
3-Lithiothiophene by treating with n-butyllithium in hexane.[3]
Derivatives of thienylenic α, ω−diformyl−α−oligothiophenes[4].
N-(2-(3-bromothiophen-2-yl)phenyl)methanesulfonamides by coupling at the 2-position with N-arylmethanesulfonamides, mediated by iodobenzene diacetate (178721).[5]
Oxidation of N-aromatic methanesulfonamides with iodobenzene diacetate in the presence of substituted thiophene promotes interesting coupling reactions in moderate to good yields.
A convenient synthesis of 3-alkylthiophenes.
Pham CV, et al.
Synthetic Communications, 16(6), 689-696 (1986)
Synthesis and characterization of 3−hexyl multi−substituted α, ω−diformyl−α−oligothiophenes (n= 3, 6, 8).
Olinga T, et al.
Macromolecular Chemistry and Physics, 198(4), 1091-1107 (1997)
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