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Merck

HTR3E

5-hydroxytryptamine (serotonin) receptor 3E, ionotropic

Synonyms:
5-HT3-E, 5-HT3E, 5-HT3c1
Species:
Human HTR3E (285242), cow HTR3E (616094), dog HTR3E (488102), sheep HTR3E (101122747), domestic cat HTR3E (101089387), Horse HTR3E (100066981), naked mole-rat Htr3e (101717686)
UniProtKB ID:
A5X5Y0, A8IKD7, E9PGF1, Q495G1, Q495G3, Q6V706, Q6V707, Q7Z6B2
Gene ID:
  • Human(285242) Summary: This locus encodes a 5-hydroxytryptamine (serotonin) receptor subunit. The encoded protein, subunit E, may play a role in neurotransmission in myenteric neurons. Genes encoding subunits C, D and E form a cluster on chromosome 3. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Feb 2012]
  • cow(616094) 5-hydroxytryptamine (serotonin) receptor 3E, ionotropic
  • dog(488102) 5-hydroxytryptamine (serotonin) receptor 3E, ionotropic
  • sheep(101122747) 5-hydroxytryptamine (serotonin) receptor 3E, ionotropic
  • domestic cat(101089387) 5-hydroxytryptamine (serotonin) receptor 3E, ionotropic
  • Horse(100066981) 5-hydroxytryptamine (serotonin) receptor 3E, ionotropic
  • naked mole-rat(101717686) 5-hydroxytryptamine (serotonin) receptor 3E, ionotropic

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Small Molecule - Agonist

Product Number
Description
Species
S1688
SR 57227A, solid,
Species
human
C144
1-(3-Chlorophenyl)biguanide hydrochloride, solid,
Species
human
M0763
Metoclopramide hydrochloride, solid,
Species
human
T104
Tropisetron monohydrochloride, solid, ≥98% (HPLC),
Species
rat, human
F112
(+)-Fenfluramine hydrochloride, ,
Species
human

Small Molecule - Allosteric Modulator

Product Number
Description
Species
D9190
DCEBIO, ≥98% (HPLC), solid,
Species
human

Small Molecule - Antagonist

Product Number
Description
Species
M0763
Metoclopramide hydrochloride, solid,
Species
human
T104
Tropisetron monohydrochloride, solid, ≥98% (HPLC),
Species
rat, human
Y0001534
Amisulpride for system suitability, European Pharmacopoeia (EP) Reference Standard,
Species
human
BP1143
Amisulpride for system suitability, British Pharmacopoeia (BP) Reference Standard,
Species
human
A0590000
Amisulpride, European Pharmacopoeia (EP) Reference Standard,
Species
human

Small Molecule - Blocker

Product Number
Description
Species
Z101
Zimelidine dihydrochloride, solid,
Species
human
T3146
Trimipramine maleate salt, ≥98% (TLC), powder,
Species
human
Q109
6-Nitroquipazine maleate salt, solid,
Species
human

Small Molecule - Inhibitor

Product Number
Description
Species
F1678
R-(−)-Fluoxetine hydrochloride, >98% (HPLC), solid,
Species
human
F1553
S-(+)-Fluoxetine hydrochloride, ≥98% (HPLC), solid,
Species
human
C7861
Citalopram hydrobromide, ≥98% (HPLC),
Species
human
C7291
Clomipramine hydrochloride, ≥98% (HPLC), powder,
Species
human
F132
Fluoxetine hydrochloride, solid,
Species
human

Small Molecule - Ligand

Product Number
Description
Species
M1514
Nω-Methyl-5-hydroxy­trypt­amine oxalate salt, ≥90% (HPLC),
Species
human

Small Molecule - Metabolite

Product Number
Description
Species
H8876
5-Hydroxyindole-3-acetic acid, ≥98% (HPLC), crystalline,
Species
human

Small Molecule - Precursor

Product Number
Description
Species
H9772
5-Hydroxy-L-tryptophan, powder,
Species
human