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Merck

HTR3D

5-hydroxytryptamine (serotonin) receptor 3D, ionotropic

Synonyms:
5HT3D
Species:
UniProtKB ID:
Gene ID:
  • Human(200909) Summary: The protein encoded this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit D of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a mitogen and a hormone. This hormone has been linked to neuropsychiatric disorders, including anxiety, depression, and migraine. Serotonin receptors causes fast and depolarizing responses in neurons following activation. The genes encoding subunits C, D and E of this type 3 receptor form a cluster on chromosome 3. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2009]
  • domestic cat(101090286) 5-hydroxytryptamine (serotonin) receptor 3D, ionotropic

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Small Molecule - Agonist

Product Number
Description
Species
SR 57227A, solid,
Species
human
1-(3-Chlorophenyl)biguanide hydrochloride, solid,
Species
human
Metoclopramide hydrochloride, solid,
Species
human
Tropisetron monohydrochloride, solid, ≥98% (HPLC),
Species
rat, human
(+)-Fenfluramine hydrochloride, ,
Species
human

Small Molecule - Allosteric Modulator

Product Number
Description
Species
DCEBIO, ≥98% (HPLC), solid,
Species
human

Small Molecule - Antagonist

Product Number
Description
Species
Metoclopramide hydrochloride, solid,
Species
human
Tropisetron monohydrochloride, solid, ≥98% (HPLC),
Species
rat, human
Amisulpride, European Pharmacopoeia (EP) Reference Standard,
Species
human
Amisulpride, ≥98% (HPLC),
Species
human
Amisulpride, British Pharmacopoeia (BP) Reference Standard,
Species
human

Small Molecule - Blocker

Product Number
Description
Species
Trimipramine maleate salt, ≥98% (TLC), powder,
Species
human
6-Nitroquipazine maleate salt, solid,
Species
human
Zimelidine dihydrochloride, solid,
Species
human

Small Molecule - Inhibitor

Product Number
Description
Species
S-(+)-Fluoxetine hydrochloride, ≥98% (HPLC), solid,
Species
human
R-(−)-Fluoxetine hydrochloride, >98% (HPLC), solid,
Species
human
Sertraline hydrochloride, ≥98% (HPLC),
Species
human
Fluvoxamine maleate, solid,
Species
human
Citalopram hydrobromide, ≥98% (HPLC),
Species
human

Small Molecule - Ligand

Product Number
Description
Species
Nω-Methyl-5-hydroxy­trypt­amine oxalate salt, ≥90% (HPLC),
Species
human

Small Molecule - Metabolite

Product Number
Description
Species
5-Hydroxyindole-3-acetic acid, ≥98% (HPLC), crystalline,
Species
human

Small Molecule - Precursor

Product Number
Description
Species
5-Hydroxy-L-tryptophan, powder,
Species
human