FLT1
fms-related tyrosine kinase 1
Synonyms:
FLT, FLT-1, VEGFR-1, VEGFR1
Species:
Human FLT1 (2321), Mouse Flt1 (14254), Rat Flt1 (54251), domestic guinea pig Flt1 (100732326), Zebrafish flt1 (544667), dog FLT1 (403727), domestic cat FLT1 (101088292), sheep FLT1 (443088), chicken FLT1 (374100), Horse FLT1 (100061940) ...More
UniProtKB ID:
Gene ID:
- Human(2321) Summary: This gene encodes a member of the vascular endothelial growth factor receptor (VEGFR) family. VEGFR family members are receptor tyrosine kinases (RTKs) which contain an extracellular ligand-binding region with seven immunoglobulin (Ig)-like domains, a transmembrane segment, and a tyrosine kinase (TK) domain within the cytoplasmic domain. This protein binds to VEGFR-A, VEGFR-B and placental growth factor and plays an important role in angiogenesis and vasculogenesis. Expression of this receptor is found in vascular endothelial cells, placental trophoblast cells and peripheral blood monocytes. Multiple transcript variants encoding different isoforms have been found for this gene. Isoforms include a full-length transmembrane receptor isoform and shortened, soluble isoforms. The soluble isoforms are associated with the onset of pre-eclampsia.[provided by RefSeq, May 2009]
- Mouse(14254) FMS-like tyrosine kinase 1
- Rat(54251) FMS-related tyrosine kinase 1
- domestic guinea pig(100732326) fms-related tyrosine kinase 1
- Zebrafish(544667) fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)
- dog(403727) fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)
- domestic cat(101088292) fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)
- sheep(443088) fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)
- chicken(374100) fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)
- Horse(100061940) fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)
- cow(503620) fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)
- Domestic Rabbit(100343352) fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)
- Horse(100033957) fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)
- naked mole-rat(101711333) fms-related tyrosine kinase 1
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-phospho-VEGFR1 (pTyr1333) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Monoclonal Anti-Vascular Endothelial Growth Factor Receptor-1 antibody produced in mouse, clone FLT-19, tissue culture supernatant,
Species Reactivity
human
Application
ELISA
immunohistochemistry
immunoprecipitation (IP)
microarray
immunohistochemistry
immunoprecipitation (IP)
microarray
Monoclonal Anti-Vascular Endothelial Growth Factor Receptor-1 antibody produced in mouse, clone FLT-11, ascites fluid,
Species Reactivity
human
Application
ELISA
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
western blot
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
western blot
Monoclonal Anti-FLT1 antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL0345, purified immunoglobulin, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
western blot
Anti-VEGFR1 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry
immunohistochemistry
Small Molecule - Inhibitor
Proteins
Product Number
Description
Species
VEGF Receptor-1 (Flt-1)/Fc Chimera from mouse, ≥90% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder, suitable for cell culture,
Species
mouse
VEGF Receptor-1 (Flt-1)/Fc Chimera human, >90% (SDS-PAGE), recombinant, expressed in baculovirus infected Sf21 cells, lyophilized powder,
Species
human