sp3-sp3 Coupling reactions in the synthesis of natural products and biologically active molecules.

sp3-sp3 Coupling reactions in the synthesis of natural products and biologically active molecules.

Natural product reports (2014-02-28)

Egor Geist, Andreas Kirschning, Thomas Schmidt

ABSTRACT

This Highlight covers the current status of relatively unexplored sp(3)-sp(3) cross-coupling reactions with particular focus on natural product and related syntheses.

MATERIALS

Product Number

Brand

Product Description

510041

Sigma-Aldrich

Raney^®-Nickel, W.R. Grace and Co. Raney^® 4200, slurry, in H₂O, active catalyst

510033

Sigma-Aldrich

Raney^®-Nickel, W.R. Grace and Co. Raney^® 2400, slurry, in H₂O, active catalyst

221678

Sigma-Aldrich

Raney^®-Nickel, W.R. Grace and Co. Raney^® 2800, slurry, in H₂O, active catalyst

268259

Sigma-Aldrich

Nickel, foil, thickness 0.125 mm, ≥99.9%

267058

Sigma-Aldrich

Nickel, wire, diam. 0.5 mm, ≥99.99% trace metals basis

203904

Sigma-Aldrich

Nickel, powder, <150 μm, 99.99% trace metals basis

GF62384328

Nickel, tube, 100mm, outside diameter 0.8mm, inside diameter 0.64mm, wall thickness 0.08mm, as drawn, 99.5%

GF18961960

Nickel, tube, 200mm, outside diameter 1.3mm, inside diameter 1.1mm, wall thickness 0.1mm, hard, 99.5%

GF70194371

Nickel, foil, 10mm disks, thickness 0.075mm, as rolled, 99.98%

GF26431871

Nickel, wire reel, 20m, diameter 0.125mm, as drawn, 99%

GF62326559

Nickel, wire reel, 20m, diameter 0.5mm, as drawn, 99%

268283

Sigma-Aldrich

Nickel, powder, <1 μm, 99.8% trace metals basis

357634

Sigma-Aldrich

Nickel, wire, diam. 0.25 mm, ≥99.9%

510068

Sigma-Aldrich

Raney^®-Nickel, W.R. Grace and Co. Raney^® 3202, slurry, in H₂O, active catalyst

267007

Sigma-Aldrich

Nickel, foil, thickness 0.25 mm, 99.995% trace metals basis

GF34555215

Nickel, wire reel, 5m, diameter 0.25mm, annealed, 99%

GF77403898

Nickel, wire reel, 1m, diameter 0.5mm, as drawn, 99.99+%

GF18587975

Nickel, sphere, 100pcs, diameter 1.0mm, precision sphere grade 200, 99%

GF22505284

Nickel, foil, 150x150mm, thickness 1.6mm, 99%

GF45846456

Nickel, wire reel, 1m, diameter 1.0mm, hard, 99.98%

GF72359017

Nickel, foil, 50x50mm, thickness 0.25mm, as rolled, 99.999%

GF44632818

Nickel, foil, light tested, 100x100mm, thickness 0.015mm, 99.9%

GF91050689

Nickel, foil, 4mm disks, thickness 0.0125mm, 99.99+%

GF19857864

Nickel, insulated wire, 2m, conductor diameter 0.025mm, insulation thickness 0.0035mm, polyimide insulation

GF19140342

Nickel, foil, 150x150mm, thickness 0.25mm, annealed, 99.98%

GF17533997

Nickel, wire reel, 100m, diameter 0.5mm, annealed, 99%

GF00207638

Nickel, wire reel, 0.2m, diameter 1.0mm, as drawn, 99.99+%

GF31900508

Nickel, foil, 50x50mm, thickness 0.125mm, as rolled, 99.99+%

GF32263354

Nickel, foil, 25x25mm, thickness 0.25mm, as rolled, 99.99+%

GF90338508

Nickel, foil, 4mm disks, thickness 0.03mm, 99.9%