1604880

Rizatriptan benzoate

United States Pharmacopeia (USP) Reference Standard

• Synonym(s): Rizatriptan benzoate salt, MK-462, N,N-Dimethyl-2-[5-(1,2,4-triazol-1-ylmethyl)-1H-indol-3-yl]ethylamine benzoate salt
• Empirical Formula (Hill Notation): C₁₅H₁₉N₅ · C₇H₆O₂
• CAS Number: 145202-66-0
• Molecular Weight: 391.47
• MDL number: MFCD00866224
• UNSPSC Code: 41116107
• PubChem Substance ID: 329751055
• NACRES: NA.24

Properties

• grade: pharmaceutical primary standard
• API family: rizatriptan
• manufacturer/tradename: USP
• application(s): pharmaceutical (small molecule)
• format: neat
• storage temp.: 2-8°C
• SMILES string: OC(=O)c1ccccc1.CN(C)CCc2c[nH]c3ccc(Cn4cncn4)cc23
• InChI: 1S/C15H19N5.C7H6O2/c1-19(2)6-5-13-8-17-15-4-3-12(7-14(13)15)9-20-11-16-10-18-20;8-7(9)6-4-2-1-3-5-6/h3-4,7-8,10-11,17H,5-6,9H2,1-2H3;1-5H,(H,8,9)
• InChI key: JPRXYLQNJJVCMZ-UHFFFAOYSA-N
• Gene Information: human ... HTR1B(3351) , HTR1D(3352)

Description

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Rizatriptan benzoate USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Rizatriptan Benzoate Orally Disintegrating Tablets
• Rizatriptan Benzoate Tablets

Biochem/physiol Actions

Rizatriptan is a serotonin 5HT-1B/1D-receptor agonist used to treat migraine.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Safety Information

• Pictograms: GHS08
• Signal Word: Danger
• Hazard Statements: H360
• Precautionary Statements: P201 - P280 - P308 + P313
• Hazard Classifications: Repr. 1B
• Storage Class Code: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable