Tropomyosin is a rigid, rod shaped protein, closely associated with actin filaments. In non-muscle cells grown in culture, tropomyosin is distributed periodically along the length of the stress fibers.
Specificity
The antibody specifically reacts with tropomyosin (typical banded pattern of stress fibers) in cultured cells and two tropomyosin bands of total chicken gizzard extract by immunoblotting.
Immunogen
smooth muscle tropomyosin from chicken gizzard.
Application
Anti-Tropomyosin antibody produced in rabbit has been used in western immunoblotting and immunofluorescence.
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Biochemical and biophysical research communications, 225(2), 427-435 (1996-08-14)
Tropomyosin is an actin-associated cytoskeletal protein expressed in muscle and non-muscle cells. There are several tropomyosin isoforms, and their cellular expression is known to be associated with transformation events caused by retroviral infection and chemical mutagens. We found that expression
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