Skip to Content
MilliporeSigma
All Photos(1)

Key Documents

SCP0169

Sigma-Aldrich

HIV-1 Tat Peptide

≥95% (HPLC), lyophilized powder

Sign Into View Organizational & Contract Pricing


About This Item

Empirical Formula (Hill Notation):
C65H124N34O13
Molecular Weight:
1589.90
UNSPSC Code:
12352202
NACRES:
NA.32

product name

HIV-TAT (48-57),

Assay

≥95% (HPLC)

form

lyophilized

composition

Peptide Content, ≥55%

storage condition

protect from light

storage temp.

−20°C

Amino Acid Sequence

Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Pro-Pro-NH2

General description

Human immunodeficiency virus (HIV)-transactivator of transcription (Tat), a regulatory protein is coded by the Tat gene of HIV-1. Tat is made up of two exons, highly conserved regions, and subtype-specific regions.

Biochem/physiol Actions

Human immunodeficiency virus (HIV)-transactivator of transcription (Tat) participates in the pathogenesis of HIV-related complications. Tat protein is also involved in HIV-related cardiac dysfunction. HIV-TAT (48-57) is used to facilitate the internalization of synthetic peptides.

Storage Class Code

11 - Combustible Solids

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

S-M Lee et al.
Clinical and experimental immunology, 161(3), 504-511 (2010-07-22)
The immune receptor expressed on myeloid cells 1 (IREM-1) has been known to regulate the activities of myeloid cells through its immunoreceptor tyrosine-based inhibition motifs (ITIMs) in its intracellular region. In order to investigate its effect on macrophage activation, a
Yanan Jiang et al.
Journal of translational medicine, 16(1), 121-121 (2018-05-10)
The human immunodeficiency virus (HIV) is a major global public health issue. HIV-related cardiovascular disease remains a leading cause of morbidity and mortality in HIV positive patients. HIV Tat is a regulatory protein encoded by tat gene of HIV-1, which
S-M Lee et al.
Clinical and experimental immunology, 167(3), 438-446 (2012-02-01)
The immune receptor expressed on myeloid cells 1 (IREM-1/CD300F) has been shown to inhibit various inflammatory processes in myeloid cells, such as macrophages and mast cells. IREM-1 exerts its inhibitory effect through its intracellular immunoreceptor tyrosine-based inhibition motifs (ITIMs). In

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service