Sigma tests the solublity of Methylprednisolone at 50 mg/ml in chloroform:methanol (1:1) yielding a clear, colorless to faint yellow solution. This product is practically insoluble in water, soluble 1 in 100 of dehydrated ethanol (10 mg/ml), slightly soluble in chloroform and ether; sparingly soluble in dioxan and methanol. It has been reported that this product is soluble in DMSO at a concentration of 100 mM. An NMR has been run using DMSO-d6 suggesting this product is soluble at 5-10 mg/ml in DMSO.
M0639
6α-Methylprednisolone
≥98%
Synonym(s):
11β,17α,21-Trihydroxy-6α-methyl-1,4-pregnadiene-3,20-dione, 6α-Methyl-11β,17α,21-trihydroxy-1,4-pregnadiene-3,20-dione, Medrol, Medrone
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About This Item
Empirical Formula (Hill Notation):
C22H30O5
CAS Number:
Molecular Weight:
374.47
Beilstein:
2340300
EC Number:
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
Pricing and availability is not currently available.
Recommended Products
biological source
synthetic
Quality Level
sterility
non-sterile
Assay
≥98%
form
powder
solubility
chloroform: methanol (1:1): 50 mg/mL, clear, colorless to faintly yellow
application(s)
cell analysis
shipped in
ambient
storage temp.
room temp
SMILES string
[H][C@@]12C[C@H](C)C3=CC(=O)C=C[C@]3(C)[C@@]1([H])[C@@H](O)C[C@@]4(C)[C@@]2([H])CC[C@]4(O)C(=O)CO
InChI
1S/C22H30O5/c1-12-8-14-15-5-7-22(27,18(26)11-23)21(15,3)10-17(25)19(14)20(2)6-4-13(24)9-16(12)20/h4,6,9,12,14-15,17,19,23,25,27H,5,7-8,10-11H2,1-3H3/t12-,14-,15-,17-,19+,20-,21-,22-/m0/s1
InChI key
VHRSUDSXCMQTMA-PJHHCJLFSA-N
Gene Information
human ... NR3C1(2908)
rat ... Nr3c1(24413)
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Application
Biochem/physiol Actions
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Repr. 1B - STOT RE 2
Target Organs
Adrenal gland,Immune system
Storage Class Code
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 2
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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