C2671
Corticotropin Releasing Factor bovine
≥90% (HPLC), Synthetic
Synonym(s):
CRF, CRH
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About This Item
Empirical Formula (Hill Notation):
C206H340N60O63S
CAS Number:
Molecular Weight:
4697.33
MDL number:
UNSPSC Code:
12352202
NACRES:
NA.32
Recommended Products
Quality Level
Assay
≥90% (HPLC)
form
powder
UniProt accession no.
storage temp.
−20°C
Gene Information
cow ... CRH(280755)
Amino Acid Sequence
Ser-Gln-Glu-Pro-Pro-Ile-Ser-Leu-Asp-Leu-Thr-Phe-His-Leu-Leu-Arg-Glu-Val-Leu-Glu-Met-Thr-Lys-Ala-Asp-Gln-Leu-Ala-Gln-Gln-Ala-His-Asn-Asn-Arg-Lys-Leu-Leu-Asp-Ile-Ala
Biochem/physiol Actions
CRF is a hypothalamic peptide that releases ACTH and endorphin from the anterior pituitary. It is also a neurotransmitter in the central nervous system, and is involved in autonomic and endocrine responses to stress.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
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Mitchell Stewart Fleming et al.
Frontiers in endocrinology, 11, 603538-603538 (2020-12-18)
We recently characterized two paralogs of the thyrotropin (TSH) beta subunit in Atlantic salmon, tshβa and tshβb, issued from teleost-specific whole genome duplication. The transcript expression of tshβb, but not of tshβa, peaks at the time of smoltification, which revealed
James Koh et al.
Journal of cellular and molecular medicine, 20(2), 351-359 (2015-12-08)
Primary hyperparathyroidism (PHPT) is a common endocrine neoplastic disorder caused by a failure of calcium sensing secondary to tumour development in one or more of the parathyroid glands. Parathyroid adenomas are comprised of distinct cellular subpopulations of variable clonal status
Jacob M Maskal et al.
Scientific reports, 11(1), 22527-22527 (2021-11-20)
In utero heat stress alters postnatal physiological and behavioral stress responses in pigs. However, the mechanisms underlying these alterations have not been determined. The study objective was to characterize the postnatal hypothalamic-pituitary-adrenal axis response of in utero heat-stressed pigs. Pigs
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