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Key Documents

82415

Sigma-Aldrich

Prunetin

≥98.0% (TLC)

Synonym(s):

4′,5-Dihydroxy-7-methoxyisoflavone

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About This Item

Empirical Formula (Hill Notation):
C16H12O5
CAS Number:
Molecular Weight:
284.26
Beilstein:
292155
EC Number:
MDL number:
UNSPSC Code:
51111800
PubChem Substance ID:
NACRES:
NA.77

Assay

≥98.0% (TLC)

form

powder

SMILES string

COc1cc(O)c2C(=O)C(=COc2c1)c3ccc(O)cc3

InChI

1S/C16H12O5/c1-20-11-6-13(18)15-14(7-11)21-8-12(16(15)19)9-2-4-10(17)5-3-9/h2-8,17-18H,1H3

InChI key

KQMVAGISDHMXJJ-UHFFFAOYSA-N

Biochem/physiol Actions

Inhibitor of both cytoplasmic and mitochondrial human liver aldehyde dehydrogenases, possibly by binding at an allosteric site.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Y Yura et al.
Archives of virology, 132(3-4), 451-461 (1993-01-01)
Genistein, an inhibitor of protein-tyrosine kinase, inhibited the replication of herpes simplex virus type 1 (HSV-1) at genistein concentrations of more than 25 microM, whereas the related compounds, which do not inhibit protein-tyrosine kinases, did not affect the replication of
Bumjung Kim et al.
Molecules (Basel, Switzerland), 23(9) (2018-09-20)
Prunetin, a component of herbal medicines and various foods, such as pea, peach, cherry, and Prunus yedoensis, is a useful pharmacological compound. We previously reported the potent vasorelaxant effect of the bark of P. yedoensis. Therefore, we investigated the vasorelaxant
Preethi Vetrivel et al.
Biomolecules, 10(7) (2020-07-28)
Gastric cancer is the common type of malignancy positioned at second in mortality rate causing burden worldwide with increasing treatment options. Prunetin (PRU) is an O-methylated flavonoid that belongs to the group of isoflavone executing beneficial activities. In the present
Su-Ling Wong et al.
Journal of natural products, 74(12), 2489-2496 (2011-12-14)
Bioassay-guided fractionation of the roots of Neolitsea daibuensis afforded three new β-carboline alkaloids, daibucarbolines A-C (1-3), three new sesquiterpenoids, daibulactones A and B (4 and 5) and daibuoxide (6), and 20 known compounds. The structures of 1-6 were determined by
Ruth N Muchiri et al.
Journal of AOAC International, 103(4), 1160-1166 (2020-11-27)
Extracts of red clover (Trifolium pratense L.) containing estrogenic and pro-estrogenic isoflavones are used in dietary supplements primarily for the management of menopausal symptoms in women. A UHPLC-MS/MS assay was developed and validated for the quantitative analysis of the six

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