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Key Documents

AB5630P

Sigma-Aldrich

Anti-Ca++ Sensing Receptor Antibody

Chemicon®, from rabbit

Synonym(s):

CaSR

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

rabbit

Quality Level

100

antibody form

affinity purified immunoglobulin

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

human

manufacturer/tradename

Chemicon®

technique(s)

ELISA: suitable
western blot: suitable

NCBI accession no.

NM_000388.2

UniProt accession no.

P41180

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

human ... CASR(846)

Specificity

Recognizes Calcium Sensing Receptor (CaSR).

Immunogen

A 20 amino acid peptide sequence near the C-terminus of human CaSR. The immunogen sequence is 90% conserved in rat/mouse and 85% in bovine.

Application

Research Category
Neuroscience
Research Sub Category
Signaling Neuroscience

Neurotransmitters & Receptors
This Anti-Ca++ Sensing Receptor Antibody is validated for use in ELISA, WB for the detection of Ca++ Sensing Receptor.
Western blot: 1-10 μg/mL using ECL.

ELISA: 0.5-1 μg/mL using 1 μg/mL control peptide (Cat. No. AG359) per well.

Optimal working dilutions must be determined by the end user.

Physical form

Affinity purified immunoglobulin. Liquid in PBS containing 0.1% BSA

Storage and Stability

Maintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Nazih L Nakhoul et al.
American journal of physiology. Gastrointestinal and liver physiology, 318(1), G144-G161 (2019-11-12)
Calcium-sensing receptor (CaSR) is the molecular sensor by which cells respond to small changes in extracellular Ca2+ concentrations. CaSR has been reported to play a role in glandular and fluid secretion in the gastrointestinal tract and to regulate differentiation and

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