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Key Documents

AB10618

Sigma-Aldrich

Anti-BAL Antibody

Chemicon®, from rabbit

Synonym(s):

B-aggressive lymphoma

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

rabbit

Quality Level

100

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

species reactivity

human

manufacturer/tradename

Chemicon®

technique(s)

immunoprecipitation (IP): suitable
western blot: suitable

NCBI accession no.

NM_031458.1

UniProt accession no.

Q8IXQ6

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

human ... PARP9(83666)

General description

BAL (B-aggressive lymphoma) is a novel risk-related gene that is expressed at significantly higher levels in fatal high-risk diffuse large B-cell lymphomas (DLB-CL) than in cured low-risk tumors. The major BAL cDNA encodes a 88 kDa nuclear protein. BAL-overexpressing B-cell lymphoma transfectants have significantly higher rates of migration than vector-only transfectants, indicating that the risk-related BAL gene promotes malignant B-cell migration.

Specificity

Reactivity has been confirmed in with human Farage non-Hodgkin′s B-cell lymphoma and human BC-1 B-lymphocyte lymphoma lysates.
Recognizes BAL.

Immunogen

Synthetic peptide derived from the C-terminal region of the short isoform of human BAL protein (B-aggressive lymphoma, poly (ADP-ribose) polymerase family member 9, PARP9).

Application

Anti-BAL Antibody is an antibody against BAL for use in IP & WB.
Research Category
Apoptosis & Cancer

Epigenetics & Nuclear Function
Research Sub Category
Tumor Markers

Transcription Factors
Western blotting: 1-3 μg/mL
Immunoprecipitation: 7 μg/ reaction

Physical form

Format: Purified
ImmunoAffinity Purified
This polyclonal antibody is supplied in 400 μL of phosphate buffered saline (pH 7.4) containing 0.1% sodium azide.

Storage and Stability

Store at -20°C in undiluted aliquots for 1 year from date of shipment.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Junji Xing et al.
Nature communications, 12(1), 2681-2681 (2021-05-13)
Innate immune cells are critical in protective immunity against viral infections, involved in sensing foreign viral nucleic acids. Here we report that the poly(ADP-ribose) polymerase 9 (PARP9), a member of PARP family, serves as a non-canonical sensor for RNA virus
Samia B Bachmann et al.
Molecular cancer, 13, 125-125 (2014-06-03)
Prostate cancer (PCa) is one of the leading causes of cancer-related mortality and morbidity in the aging male population and represents the most frequently diagnosed malignancy in men around the world. The Deltex (DTX)-3-like E3 ubiquitin ligase (DTX3L), also known

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