12-523

GST, 6 His-tagged

• Synonym(s): GST Fusion Protein
• UNSPSC Code: 12352204
• eCl@ss: 32160405
• NACRES: NA.41

Properties

• form: liquid
• Quality Level: 100
• manufacturer/tradename: Upstate^®
• technique(s): affinity chromatography: suitable
• NCBI accession no.: NM_000852.2
• UniProt accession no.: P09211
• shipped in: dry ice

Description

General description

Glutathione S-transferase (GST) belongs to three families of proteins distinguished as cytosolic, mitochondrial, and microsomal GST. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: α, κ, μ, ω, π, σ, θ, and ζ. This product is a C-terminal 6 histidine-tagged, recombinant full-length glutathione S-transferase (GST).

Biochem/physiol Actions

Glutathione S-transferases (GSTs) are a family of enzymes that play an important role in phase II detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. The glutathione S-transferase pi gene (GSTP1) is a polymorphic gene encoding active, functionally different GSTP1 variant proteins that are thought to function in xenobiotic metabolism and play a role in susceptibility to cancer, and other diseases.

Physical form

50mM Tris-HCl, pH 8, 150mM NaCl, 20% glycerol

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 2