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Key Documents

07-667

Sigma-Aldrich

Anti-APP Antibody

Upstate®, from rabbit

Synonym(s):

Anti-AAA, Anti-ABPP, Anti-AD1, Anti-APPI, Anti-CTFgamma, Anti-CVAP, Anti-PN-II, Anti-PN2, Anti-alpha-sAPP, Anti-preA4

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

rabbit

Quality Level

100

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

human, rat, mouse

species reactivity (predicted by homology)

chimpanzee (based on 100% sequence homology), primate (based on 100% sequence homology)

manufacturer/tradename

Upstate®

technique(s)

immunoprecipitation (IP): suitable
western blot: suitable

isotype

IgG

NCBI accession no.

NM_000484.2
NM_201413.1
NM_201414.1

UniProt accession no.

P05067

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... APP(351)

Specificity

APP

Immunogen

synthetic peptide corresponding to amino acids 44-61 of human Amyloid Precursor Protein (APP)

Application

Anti-APP Antibody detects level of APP & has been published & validated for use in IP & WB.
Research Category
Neuroscience
Research Sub Category
Ubiquitin & Ubiquitin Metabolism

Neurodegenerative Diseases

Quality

Routinely evaluated by immunoblot.

Target description

110kDa

Physical form

ImmunoAffinity Purified
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.05% sodium azide.

Storage and Stability

Stable for 1 year at 2-8°C from date of receipt.

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Distinct presenilin-dependent and presenilin-independent gamma-secretases are responsible for total cellular Abeta production.
Wilson, Christina A, et al.
Journal of Neuroscience Research, 74, 361-369 (2003)
Structure and function of amyloid in Alzheimer's disease.
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Progress in Neurobiology, 74, 323-349 (2004)
CSF markers for Alzheimer's disease: total tau, phospho-tau and Abeta42.
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