W269905

6-Methylcoumarin

≥99%, FCC, FG

• Synonym(s): 6-methylchromen-2-one, Cocodescol, Pralina, Toncair, Toncarine
• Empirical Formula (Hill Notation): C₁₀H₈O₂
• CAS Number: 92-48-8
• Molecular Weight: 160.17
• FEMA Number: 2699
• EC Number: 202-158-8
• Council of Europe no.: 579
• MDL number: MFCD00006875
• UNSPSC Code: 12164502
• PubChem Substance ID: 24901267
• Flavis number: 13.012
• NACRES: NA.21

Properties

• biological source: synthetic
• Quality Level: 400
• grade: FG; Halal; Kosher
• Agency: meets purity specifications of JECFA
• reg. compliance: EU Regulation 1334/2008 & 178/2002; FCC
• Assay: ≥99%
• bp: 303 °C/725 mmHg (lit.)
• mp: 73-76 °C (lit.)
• application(s): flavors and fragrances
• Documentation: see Safety & Documentation for available documents
• food allergen: no known allergens
• Organoleptic: coconut; creamy; sage; vanilla
• SMILES string: Cc1ccc2OC(=O)C=Cc2c1
• InChI: 1S/C10H8O2/c1-7-2-4-9-8(6-7)3-5-10(11)12-9/h2-6H,1H3
• InChI key: FXFYOPQLGGEACP-UHFFFAOYSA-N

Description

Application

• Development of Sustainable Insecticide Candidates for Protecting Pollinators: Insight into the Bioactivities, Selective Mechanism of Action and QSAR of Natural Coumarin Derivatives against Aphids.: This study explores the potential of 6-Methylcoumarin and other natural coumarin derivatives as sustainable insecticides, highlighting their bioactivities and selective mechanism of action. The research aims to protect pollinators while targeting aphids, providing a promising alternative to conventional pesticides (Zhou et al., 2023).


• Conductive Vial Electromembrane Extraction of Opioids from Oral Fluid.: This research presents a novel method using conductive vial electromembrane extraction for isolating opioids from oral fluid. While the primary focus is on opioids, the study utilizes 6-Methylcoumarin as a key component in the extraction process, showcasing its versatility in analytical chemistry applications (Skaalvik et al., 2023).


• 6-Methylcoumarin Promotes Melanogenesis through the PKA/CREB, MAPK, AKT/PI3K, and GSK3β/β-Catenin Signaling Pathways.: This article investigates the role of 6-Methylcoumarin in promoting melanogenesis, detailing the molecular pathways involved. The findings suggest potential applications in dermatology and cosmetic science, particularly in skin pigmentation treatments (Kim et al., 2023).


• Recursively Positive and Negative Chemotaxis Coupling with Reaction Kinetics in Self-Organized Inanimate Motion.: This research delves into the chemotactic behavior of inanimate particles, using 6-Methylcoumarin in the reaction kinetics studies. The study contributes to the understanding of self-organizing systems, with implications for material science and biophysics (Matsuo et al., 2023).

Biochem/physiol Actions

Taste at 5 ppm

Safety Information

• Pictograms: GHS08,GHS07
• Signal Word: Danger
• Hazard Statements: H302,H317,H334
• Precautionary Statements: P280 - P301 + P312 + P330 - P302 + P352
• Hazard Classifications: Acute Tox. 4 Oral - Resp. Sens. 1 - Skin Sens. 1
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves