Skip to Content
MilliporeSigma
All Photos(2)

Documents

D102008

Sigma-Aldrich

1,3-Difluorobenzene

≥99%

Synonym(s):

1,3-Bisfluorobenzene, 1,3-Difluorobenzene, 2,4-Difluorobenzene, m-Difluorobenzene

Sign Into View Organizational & Contract Pricing
All Photos(2)

About This Item

Empirical Formula (Hill Notation):
C6H4F2
CAS Number:
372-18-9
Molecular Weight:
114.09
Beilstein:
1904537
EC Number:
206-746-5
MDL number:
MFCD00000327
UNSPSC Code:
12352100
PubChem Substance ID:
24893323
NACRES:
NA.22

Assay

≥99%

form

liquid

refractive index

n20/D 1.438 (lit.)

bp

82 °C (lit.)

density

1.163 g/mL at 25 °C (lit.)

SMILES string

Fc1cccc(F)c1

InChI

1S/C6H4F2/c7-5-2-1-3-6(8)4-5/h1-4H

InChI key

UEMGWPRHOOEKTA-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Pictograms

Flame
GHS02

Signal Word

Danger

Hazard Statements

H225

Precautionary Statements

P210

Hazard Classifications

Flam. Liq. 2

Storage Class Code

3 - Flammable liquids

WGK

WGK 1

Flash Point(F)

35.6 °F

Flash Point(C)

2 °C

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

D Gala et al.
Journal of pharmaceutical sciences, 81(12), 1199-1203 (1992-12-01)
Alpha-Hydroxyaryl ketones such as 2-hydroxypropiophenone and 1-(2,4-difluorophenyl)-2-hydroxy-1-propanone, the key intermediates in the preparation of antifungal agents, decompose into oxidized, rearranged, and condensed products. These products were isolated and characterized. The possible mechanisms for the formation of the products are discussed.
Aujin Kim et al.
The Journal of organic chemistry, 71(5), 2170-2172 (2006-02-25)
A short, high-yielding synthesis of differentially substituted resorcinol derivatives has been developed that utilizes 1,3-difluorobenzene as the starting material and employs sequential nucleophilic aromatic substitution (S(N)Ar) reactions to generate desymmetrized products. The scope and limitations of the second S(N)Ar reaction

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service