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764167

Sigma-Aldrich

Alkyne-PEG5-acid

Synonym(s):

Polyethylene glycol, Acetylene-PEG5-acid

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About This Item

Empirical Formula (Hill Notation):
C14H24O7
CAS Number:
1245823-51-1
Molecular Weight:
304.34
MDL number:
MFCD22201536
UNSPSC Code:
12352106
PubChem Substance ID:
329767102
NACRES:
NA.22

form

liquid

Quality Level

100

reaction suitability

reaction type: click chemistry
reagent type: cross-linking reagent

functional group

alkyne
carboxylic acid

storage temp.

−20°C

SMILES string

C#CCOCCOCCOCCOCCOCCC(O)=O

InChI

1S/C14H24O7/c1-2-4-17-6-8-19-10-12-21-13-11-20-9-7-18-5-3-14(15)16/h1H,3-13H2,(H,15,16)

InChI key

GWIACWQVTBMVEI-UHFFFAOYSA-N

Application

Alkyne-PEG5-acid may be used in the synthesis of peptide nucleic acid (PNA) oligomers that can conjugate with vitamin B12 via Cu-catalyzed 1,3-dipolar cycloaddition in order to study if vitamin B12 to transport PNA oligonucleotides into bacterial cells.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H319

Precautionary Statements

P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Vitamin B 12 as a carrier of peptide nucleic acid (PNA) into bacterial cells.
Rownicki M, et al.
Scientific Reports, 7(1), 7644-7644 (2017)

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