Skip to Content
MilliporeSigma
All Photos(1)

Documents

209538

Sigma-Aldrich

4-Fluorobenzyl bromide

97%

Synonym(s):

α-Bromo-4-fluorotoluene, 1-Bromomethyl-4-fluorobenzene

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Linear Formula:
FC6H4CH2Br
CAS Number:
459-46-1
Molecular Weight:
189.02
Beilstein:
636507
EC Number:
207-291-5
MDL number:
MFCD00000359
UNSPSC Code:
12352100
PubChem Substance ID:
24852574
NACRES:
NA.22

Assay

97%

form

liquid

refractive index

n20/D 1.547 (lit.)

bp

85 °C/15 mmHg (lit.)

density

1.517 g/mL at 25 °C (lit.)

SMILES string

Fc1ccc(CBr)cc1

InChI

1S/C7H6BrF/c8-5-6-1-3-7(9)4-2-6/h1-4H,5H2

InChI key

NVNPLEPBDPJYRZ-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Application

4-Fluorobenzyl bromide was used in the preparation of:
  • 3-acetyl-1-(4-fluorobenzyl)-4-hydroxy-1H-indole
  • 1-(4-fluorobenzyl)-5-(pyrrolidine-1-sulfonyl)isatin
  • (S)-1-(4-fluorobenzyl)-5-(2-(4-fluorophenoxymethyl)pyrrolidine-1-sulfonyl)isatin
  • 8-bromo 9-(4-fluorobenzyl) adenine
  • 8-bromo 3-(4-fluorobenzyl) adenine

Pictograms

Corrosion
GHS05

Signal Word

Danger

Hazard Statements

H314

Hazard Classifications

Skin Corr. 1B

Storage Class Code

8A - Combustible corrosive hazardous materials

WGK

WGK 3

Flash Point(F)

>235.4 °F - closed cup

Flash Point(C)

> 113 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Graham Smith et al.
Journal of medicinal chemistry, 51(24), 8057-8067 (2008-12-04)
Imaging of programmed cell death (apoptosis) is important in the assessment of therapeutic response in oncology and for diagnosis in cardiac and neurodegenerative disorders. The executioner caspases 3 and 7 ultimately effect cellular death, thus providing selective molecular targets for
Xingnan Li et al.
Bioorganic & medicinal chemistry, 14(16), 5742-5755 (2006-06-07)
Because of its essential role in HIV replication and lack of human counterpart, HIV integrase is an attractive target for the development of novel anti-AIDS agents. Among the recently developed integrase inhibitors, only the alpha,gamma-diketo acid (DKA) compounds were biologically
Laura De Luca et al.
ChemMedChem, 4(8), 1311-1316 (2009-07-01)
The cellular protein lens epithelium-derived growth factor, or transcriptional coactivator p75 (LEDGF/p75), plays a crucial role in HIV integration. The protein-protein interactions (PPIs) between HIV-1 integrase (IN) and its cellular cofactor LEDGF/p75 may therefore serve as targets for the development
Kathleen E Prosser et al.
Journal of inorganic biochemistry, 167, 89-99 (2016-12-05)
The Cu(II) complex CuCl
Ihor Kulai et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 23(63), 16066-16077 (2017-08-31)
Eight alkyl triarylstannanecarbodithioates were synthesized starting from the corresponding triarylstannyl chlorides. They were fully characterized by IR and
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service