1370000

Loperamide hydrochloride

United States Pharmacopeia (USP) Reference Standard

• Synonym(s): 4-(p-Chlorophenyl)-4-hydroxy-N,N-dimethyl-α,α-diphenyl-1-piperidinebutyramide hydrochloride
• Empirical Formula (Hill Notation): C₂₉H₃₃ClN₂O₂ · HCl
• CAS Number: 34552-83-5
• Molecular Weight: 513.50
• MDL number: MFCD00058581
• NACRES: NA.24
• PubChem Substance ID: 329750255
• UNSPSC Code: 41116107

Properties

• grade: pharmaceutical primary standard
• agency: USP
• API family: loperamide
• manufacturer/tradename: USP
• application(s): pharmaceutical (small molecule)
• format: neat
• SMILES string: Cl.CN(C)C(=O)C(CCN1CCC(O)(CC1)c2ccc(Cl)cc2)(c3ccccc3)c4ccccc4
• InChI: 1S/C29H33ClN2O2.ClH/c1-31(2)27(33)29(24-9-5-3-6-10-24,25-11-7-4-8-12-25)19-22-32-20-17-28(34,18-21-32)23-13-15-26(30)16-14-23;/h3-16,34H,17-22H2,1-2H3;1H
• InChI key: PGYPOBZJRVSMDS-UHFFFAOYSA-N
• Gene Information: human ... OPRM1(4988)

Description

Application

Loperamide hydrochloride USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Loperamide Hydrochloride Tablets
• Loperamide Hydrochloride Capsules
• Loperamide Hydrochloride Oral Solution

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Safety Information

• pictograms: GHS06
• signalword: Danger
• hcodes: H301
• Hazard Classifications: Acute Tox. 3 Oral
• Storage Class: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• pcodes: P264 - P270 - P301 + P310 + P330 - P405 - P501