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SML2532

Jedi2

≥98% (HPLC)

Synonym(s):

2-Methyl-5-(2-thienyl)-3-furancarboxylic acid

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About This Item

Empirical Formula (Hill Notation):
C10H8O3S
CAS Number:
651005-90-2
Molecular Weight:
208.23
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
MFCD01569561
Assay:
≥98% (HPLC)
Form:
powder
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assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

2-8°C

SMILES string

[s]1c(ccc1)c2[o]c(c(c2)C(=O)O)C

InChI

1S/C10H8O3S/c1-6-7(10(11)12)5-8(13-6)9-3-2-4-14-9/h2-5H,1H3,(H,11,12)

InChI key

YXDCRSXNEOKXDE-UHFFFAOYSA-N

Biochem/physiol Actions

Jedi2 is an activator of the mechanosensitive Piezo1 channel that binds at a different place from Yoda1. It exhibits long-range allosteric gating, activating Piezo1 through the extracellular side of its peripheral blade-like structure rather than the C-terminal extracellular domain of the pore.
Piezo1 channel activator

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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