A quality control test for the range of polymer length is not conducted for this product. Historical data measured the molecular weight by low angle laser light scattering (LALLS), noting an average molecular weight that varied greatly from lot to lot, with values as low as 100 kDa and as high as greater than 600 kDa. Additionally, historical data indicated a range of 600-3000 base pairs by migration on acrylamide gel.
P9528
Polyuridylic acid potassium salt
Synonym(s):
Poly(U) potassium salt
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About This Item
Assay:
≥98% (TLC)
Form:
lyophilized powder
Solubility:
water: 19.60-20.40 mg/mL, clear to slightly hazy, colorless
Storage temp.:
−20°C
Pricing and availability is not currently available.
assay
≥98% (TLC)
Quality Segment
form
lyophilized powder
solubility
water: 19.60-20.40 mg/mL, clear to slightly hazy, colorless
storage temp.
−20°C
SMILES string
[P](=O)(OC[C@H]1O[C@H]([C@@H]([C@@H]1O)O)[n]2[c]([nH][c](cc2)=O)=O)(O)O
InChI
1S/C9H13N2O9P/c12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(20-8)3-19-21(16,17)18/h1-2,4,6-8,13-14H,3H2,(H,10,12,15)(H2,16,17,18)/t4-,6-,7-,8-/m1/s1
InChI key
DJJCXFVJDGTHFX-XVFCMESISA-N
Application
Polyuridylic acid (Poly(U)), a homopolymer of uridine, is used as a single-stranded RNA model compound often in comparison with other ssRNA model oligonucleotides such as Poly(I) and Poly(C) to study processes that are dependent upon ssRNA regulation such as Toll-like receptor regulation. Poly(U) is used as an effective agonist for TLR7.
Preparation Note
Prepared from UDP using polynucleotide phosphorylase.
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This Item | |||
|---|---|---|---|
| Quality Level 200 | Quality Level 200 | Quality Level 200 | Quality Level 300 |
| form lyophilized powder | form lyophilized powder | form lyophilized powder | form powder |
| assay ≥98% (TLC) | assay ≥98% (TLC) | assay ≥95% (TLC) | assay ≥98% (enzymatic) |
| solubility water: 19.60-20.40 mg/mL, clear to slightly hazy, colorless | solubility water: 4.80-5.20 mg/mL, clear to hazy, colorless to faintly yellow | solubility water: 19.60-20.40 mg/mL, clear to slightly hazy, colorless to light yellow | solubility water: 100 mg/mL, clear, colorless to faintly yellow |
| storage temp. −20°C | storage temp. −20°C | storage temp. −20°C | storage temp. 2-8°C |
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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What is the range of polymer lengths in this product?
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What is the the molecular weight of this product?
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This product is a polymer, and the molecular weight may vary.
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