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P3496

(+/-)-8-Prenylnaringenin

EGF signaling inhibitor, powder

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About This Item

Empirical Formula (Hill Notation):
C20H20O5
Molecular Weight:
340.37
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.56
MDL number:
Form:
powder
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Product Name

(+/-)-8-Prenylnaringenin, Plant-derived estrogen receptor ligand

form

powder

storage temp.

−20°C

SMILES string

C\C(C)=C\Cc1c(O)cc(O)c2C(=O)CC(Oc12)c3ccc(O)cc3

InChI

1S/C20H20O5/c1-11(2)3-8-14-15(22)9-16(23)19-17(24)10-18(25-20(14)19)12-4-6-13(21)7-5-12/h3-7,9,18,21-23H,8,10H2,1-2H3

InChI key

LPEPZZAVFJPLNZ-UHFFFAOYSA-N

Biochem/physiol Actions

8-Prenylnaringenin, a strong plant-derived estrogen receptor ligand, is a phytoestrogen that inhibits multidrug resistance-associated transporters, P-glycoprotein and MRP1. 8-Prenylnaringenin also inhibits EGF signaling at the level of phosphatidylinositol-3-OH kinase ((PI(3)K))activity.

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This Item
PHL89886I1786PHL80520
form

powder

form

-

form

powder

form

-

Quality Level

200

Quality Level

-

Quality Level

100

Quality Level

-

storage temp.

−20°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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