M8386

α,β-Methyleneadenosine 5′-diphosphate sodium salt

CD73 inhibitor

• Synonym(s): AMP-CP
• Empirical Formula (Hill Notation): C₁₁H₁₇N₅O₉P₂
• CAS Number: 104835-70-3
• Molecular Weight: 425.23
• MDL number: MFCD00070019
• UNSPSC Code: 41106305
• PubChem Substance ID: 24897249
• NACRES: NA.51

Properties

• biological source: synthetic (organic)
• Assay: ≥98% (HPLC)
• form: powder
• solubility: water: 50 mg/mL, clear to slightly hazy, colorless
• storage temp.: −20°C
• SMILES string: [Na].Nc1ncnc2n(cnc12)C3OC(COP(O)(=O)CP(O)(O)=O)C(O)C3O
• InChI: 1S/C11H17N5O9P2.Na.H/c12-9-6-10(14-2-13-9)16(3-15-6)11-8(18)7(17)5(25-11)1-24-27(22,23)4-26(19,20)21;;/h2-3,5,7-8,11,17-18H,1,4H2,(H,22,23)(H2,12,13,14)(H2,19,20,21);;
• InChI key: HEBWZOPLDYDXPJ-UHFFFAOYSA-N

Description

Application

α,β-Methyleneadenosine 5′-diphosphate sodium salt has been used as an ectonucleotidase/CD73 inhibitor to characterize the mode of adenosine production and as an inhibitor for in vitro studies.

Biochem/physiol Actions

α, β-Methyleneadenosine 5′-diphosphate (AMP-CP) is an ADP analog that as an ability to inhibit ectonucleotidase/ CD73 inhibitor and is used to study adenosinergic signaling regulation via CD73/ecto-5′-nucleotidase.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable