L3271

Lys-Tyr-Lys acetate salt

≥97% (HPLC)

• Synonym(s): Lysyltyrosyllysine, acetate
• Empirical Formula (Hill Notation): C₂₁H₃₅N₅O₅ · xC₂H₄O₂
• Molecular Weight: 437.53 (free base basis)
• NACRES: NA.26
• PubChem Substance ID: 24896335
• UNSPSC Code: 12352209
• MDL number: MFCD00079406

Properties

• assay: ≥97% (HPLC)
• form: powder
• color: white to off-white
• storage temp.: −20°C
• SMILES string: CC(O)=O.NCCCC[C@H](N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCCN)C(O)=O
• InChI: 1S/C21H35N5O5.C2H4O2/c22-11-3-1-5-16(24)19(28)26-18(13-14-7-9-15(27)10-8-14)20(29)25-17(21(30)31)6-2-4-12-23;1-2(3)4/h7-10,16-18,27H,1-6,11-13,22-24H2,(H,25,29)(H,26,28)(H,30,31);1H3,(H,3,4)/t16-,17-,18-;/m0./s1
• InChI key: OXXOYNFTOCTMGG-UVJOBNTFSA-N

Description

Application

Lysyltyrosyllysine (Lys-Tyr-Lys, KYK) is used together with uracil DNA glycosylase to quantify uracil. Lysyltyrosyllysine is also used as a model peptide to study free radical oxidation and electron capture mechanisms.

Biochem/physiol Actions

Tripeptide can induce nicks at apurinic/apyrimidinic sites in circular DNA.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)