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G3915

Sigma-Aldrich

Gly-Gly

BioPerformance Certified, suitable for cell culture, ≥99%

Synonym(s):

Diglycine, Glycyl-glycine

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About This Item

Linear Formula:
NH2CH2CONHCH2COOH
CAS Number:
556-50-3
Molecular Weight:
132.12
Beilstein:
1765223
EC Number:
209-127-8
MDL number:
MFCD00008130
UNSPSC Code:
12161700
PubChem Substance ID:
24894917
NACRES:
NA.25

grade

BioPerformance Certified

Assay

≥99%

form

powder

technique(s)

cell culture | mammalian: suitable

impurities

endotoxin and total aerobic microbial count, tested

color

white

useful pH range

7.5-8.9

pKa (25 °C)

8.2

mp

255-260 °C

cation traces

heavy metals (as Pb): ≤5 ppm

application(s)

diagnostic assay manufacturing

foreign activity

DNase, RNase, NICKase and protease, none detected

SMILES string

NCC(=O)NCC(O)=O

InChI

1S/C4H8N2O3/c5-1-3(7)6-2-4(8)9/h1-2,5H2,(H,6,7)(H,8,9)

InChI key

YMAWOPBAYDPSLA-UHFFFAOYSA-N

Gene Information

human ... SLC15A1(6564)

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Application


  • Flavor enhancement during the drying of scallop (Patinopecten yessoensis) as revealed by integrated metabolomic and lipidomic analysis.: This study examines the role of Gly-Gly in the flavor enhancement process during the drying of scallops. By using integrated metabolomic and lipidomic analysis, the research identifies key biochemical pathways involved in flavor formation, highlighting the significance of Gly-Gly in the food industry (Wang et al., 2024).

  • A serum metabolomics-based profile in low bone mineral density postmenopausal women.: The research identifies metabolic markers, including Gly-Gly, that are associated with low bone mineral density in postmenopausal women, contributing to the understanding of osteoporosis and potential biomarkers for early diagnosis (Miyamoto et al., 2017).

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Lasse Jenner et al.
Proceedings of the National Academy of Sciences of the United States of America, 110(10), 3812-3816 (2013-02-23)
Here we present an X-ray crystallography structure of the clinically relevant tigecycline antibiotic bound to the 70S ribosome. Our structural and biochemical analysis indicate that the enhanced potency of tigecycline results from a stacking interaction with nucleobase C1054 within the
Francis Impens et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(34), 12432-12437 (2014-08-13)
SUMOylation is an essential ubiquitin-like modification involved in important biological processes in eukaryotic cells. Identification of small ubiquitin-related modifier (SUMO)-conjugated residues in proteins is critical for understanding the role of SUMOylation but remains experimentally challenging. We have set up a
Namrata D Udeshi et al.
Molecular & cellular proteomics : MCP, 12(3), 825-831 (2012-12-26)
Detection of endogenous ubiquitination sites by mass spectrometry has dramatically improved with the commercialization of anti-di-glycine remnant (K-ε-GG) antibodies. Here, we describe a number of improvements to the K-ε-GG enrichment workflow, including optimized antibody and peptide input requirements, antibody cross-linking
P B Armentrout et al.
Journal of the American Society for Mass Spectrometry, 23(4), 621-631 (2011-09-29)
We present a full computational description of the fragmentation reactions of protonated diglycine (H(+)GG). Relaxed potential energy surface scans performed at B3LYP/6-31 G(d) or B3LYP/6-311 + G(d,p) levels are used to map the reaction coordinate surfaces and identify the transition states (TSs) and
P B Armentrout et al.
Journal of the American Society for Mass Spectrometry, 23(4), 632-643 (2011-09-29)
We present a full molecular description of fragmentation reactions of protonated diglycine (H(+)GG) by studying their collision-induced dissociation (CID) with Xe using a guided ion beam tandem mass spectrometer (GIBMS). Analysis of the kinetic energy-dependent CID cross sections provides the
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