D127

Dextrorphan tartrate

NMDA-receptor antagonist, powder

• Synonym(s): (+)-3-Hydroxy-N-methylmorphinan (+)-tartrate salt, Dextrorphan D-tartrate
• Empirical Formula (Hill Notation): C₁₇H₂₃NO · C₄H₆O₆
• CAS Number: 143-98-6
• Molecular Weight: 407.46
• MDL number: MFCD00151495
• UNSPSC Code: 12352200
• PubChem Substance ID: 24277974
• NACRES: NA.32

Properties

• Product Name: Dextrorphan tartrate, powder
• description: Drug Control: Kábítószer / Narcotic Drug (Hungary), 78/2022. (XII. 28.) BM rendelet
• Quality Level: 200
• form: powder
• drug control: Kábítószer / Narcotic Drug (Hungary), 78/2022. (XII. 28.) BM rendelet
• color: white
• solubility: H₂O: >10 mg/mL
• SMILES string: O[C@@H]([C@H](O)C(O)=O)C(O)=O.CN1CC[C@@]23CCCC[C@@H]2[C@@H]1Cc4ccc(O)cc34
• InChI: 1S/C17H23NO.C4H6O6/c1-18-9-8-17-7-3-2-4-14(17)16(18)10-12-5-6-13(19)11-15(12)17;5-1(3(7)8)2(6)4(9)10/h5-6,11,14,16,19H,2-4,7-10H2,1H3;1-2,5-6H,(H,7,8)(H,9,10)/t14-,16+,17+;1-,2-/m10/s1
• InChI key: RWTWIZDKEIWLKQ-FEBOIHDFSA-N
• Gene Information: human ... GRIN1(2902), GRIN2A(2903), GRIN2B(2904), GRIN2C(2905), GRIN2D(2906), GRINA(2907)

Description

Application

Dextrorphan tartrate has been used to study its effects on blood glucose levels by targeting pancreatic islets.

Biochem/physiol Actions

Dextrorphan is a noncompetitive NMDA glutamate receptor antagonist that attenuates glutamate neurotoxicity in cortical cell cultures.

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H302
• Hazard Classifications: Acute Tox. 4 Oral
• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves