A0972

Apolipoprotein A-II from human plasma

≥95% (SDS-PAGE), buffered aqueous solution

• Synonym(s): Apo A-II
• UNSPSC Code: 12352202
• NACRES: NA.32
• MDL number: MFCD00132612

Properties

• biological source: human plasma
• Quality Segment: 200
• assay: ≥95% (SDS-PAGE)
• form: buffered aqueous solution
• mol wt: 17.38 kDa
• UniProt accession no.: P02652
• shipped in: dry ice
• storage temp.: −20°C
• Gene Information: human ... APOA2(336)

Description

General description

Forms dimers in aqueous solutions with an association constant of 5 × 10⁴ M^-1. The association is accompanied by an enhancement of ~35% in α-helical content.

Application

Apo A-II constitutes ~20% of the protein moiety of high density lipoprotein (HDL).

Biochem/physiol Actions

Unlike Apo A-I, Apo A-II possesses no activating properties for lectin-cholesterol acyltransferase (LCAT). Furthermore, it was found that Apo A-II inhibits the activation of LCAT by Apo A-I.

Physical form

Solution in 10 mM ammonium bicarbonate.

Disclaimer

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

Safety Information

• Storage Class: 10 - Combustible liquids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable