A0972
Apolipoprotein A-II from human plasma
≥95% (SDS-PAGE), buffered aqueous solution
Synonym(s):
Apo A-II
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About This Item
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biological source
human plasma
Quality Level
Assay
≥95% (SDS-PAGE)
form
buffered aqueous solution
mol wt
17.38 kDa
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
Gene Information
human ... APOA2(336)
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General description
Forms dimers in aqueous solutions with an association constant of 5 × 104 M-1. The association is accompanied by an enhancement of ~35% in α-helical content.
Application
Apo A-II constitutes ~20% of the protein moiety of high density lipoprotein (HDL).
Biochem/physiol Actions
Unlike Apo A-I, Apo A-II possesses no activating properties for lectin-cholesterol acyltransferase (LCAT). Furthermore, it was found that Apo A-II inhibits the activation of LCAT by Apo A-I.
Physical form
Solution in 10 mM ammonium bicarbonate.
Disclaimer
RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.
Storage Class Code
10 - Combustible liquids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
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Effect of disulfide cleavage on the molecular weight of one of the major polypeptides of human serum high density lipoprotein.
A M. Scanu et al.
FEBS letters, 18(2), 305-307 (1971-11-01)
Cécile Voisset et al.
The Journal of biological chemistry, 280(9), 7793-7799 (2005-01-06)
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