N7889

Nicergoline

analytical standard, for drug analysis

• Synonym(s): 5-Bromonicotinic acid 10-methoxy-1,6-dimethylergoline-8-methyl ester
• Empirical Formula (Hill Notation): C₂₄H₂₆BrN₃O₃
• CAS Number: 27848-84-6
• Molecular Weight: 484.39
• EC Number: 248-694-6
• MDL number: MFCD00869626
• UNSPSC Code: 41116107
• PubChem Substance ID: 329818675
• NACRES: NA.24

Properties

• grade: analytical standard
• Quality Level: 100
• Assay: ≥97% (TLC)
• technique(s): HPLC: suitable; gas chromatography (GC): suitable
• application(s): forensics and toxicology; pharmaceutical (small molecule); veterinary
• format: neat
• storage temp.: 2-8°C
• SMILES string: [H][C@@]12Cc3cn(C)c4cccc(c34)[C@]1(C[C@@H](COC(=O)c5cncc(Br)c5)CN2C)OC
• InChI: 1S/C24H26BrN3O3/c1-27-13-17-8-21-24(30-3,19-5-4-6-20(27)22(17)19)9-15(12-28(21)2)14-31-23(29)16-7-18(25)11-26-10-16/h4-7,10-11,13,15,21H,8-9,12,14H2,1-3H3/t15-,21-,24+/m1/s1
• InChI key: YSEXMKHXIOCEJA-FVFQAYNVSA-N

Description

General description

Nicergoline is an ergot derivative, which may be used in the treatment of affective, cognitive and behavioral disorders seen in older people. It is an α -adrenergic antagonist that may be used for companion animals like cats and dogs to treat, behavioral disorders, problems with aging, excessive vocaliztion and restessness.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem/physiol Actions

Cerebral and peripheral vasodilator

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H302
• Hazard Classifications: Acute Tox. 4 Oral
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves