MABC150

Anti-LDH-A Antibody, clone 5D2.1

clone 5D2.1, from mouse

• Synonym(s): L-lactate dehydrogenase A chain, LDH-A, Cell proliferation-inducing gene 19 protein, LDH muscle subunit, LDH-M, Renal carcinoma antigen NY-REN-59
• UNSPSC Code: 12352203
• NACRES: NA.41
• eCl@ss: 32160702
• Conjugate: unconjugated
• Clone: 5D2.1, monoclonal
• Application: IHC, WB
• Citations: 2

Properties

• biological source: mouse
• Quality Segment: 100
• conjugate: unconjugated
• antibody form: purified immunoglobulin
• antibody product type: primary antibodies
• clone: 5D2.1, monoclonal
• species reactivity: human
• technique(s): immunohistochemistry: suitable, western blot: suitable
• isotype: IgG2aκ
• NCBI accession no.: NP_001128711
• UniProt accession no.: P00338
• shipped in: wet ice
• target post-translational modification: unmodified
• Gene Information: human ... LDHA(3939)

Description

General description

L-lactate dehydrogenase A chain (LDHA), also known as Cell proliferation-inducing gene 19 protein, LDH muscle subunit, LDH-M, Renal carcinoma antigen NY-REN-59, and encoded by the gene name LDHA/ PIG19, is a member of the LDH/MDH superfamily and LDH family. Mutations in LDHA have been assoicated with Glycogen storage disease 11 (GSD11), which is a metabolic disorder that results in exertional myoglobinuria, pain, cramps and easy fatigue.

~37 kDa observed

Immunogen

KLH-conjugated linear peptide corresponding to human LDH-A.

Application

Anti-LDH-A, clone 5D2.1 is an antibody against LDH-A for use in WB, IH.

Immunohistochemistry Analysis: A 1:1,000 dilution from a representative lot detected LDH-A in human breast cancer sections and human kidney tissue.

Research Category
Apoptosis & Cancer

Research Sub Category
Apoptosis - Additional

Physical form

Format: Purified

Protein G Purified

Purified mouse monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Preparation Note

Stable for 1 year at 2-8°C from date of receipt.

Analysis Note

Evaluated by Western Blotting in HeLa cell lysate.

Western Blotting Analysis: 0.5 µg/mL of this antibody detected LDH-A in 10 µg of HeLa cell lysate.

Other Notes

Concentration: Please refer to lot specific datasheet.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable