Skip to Content
Merck
All Photos(1)

Documents

HPLX1-115SP

Millipore

MILLIPLEX® PLEXpedition Magnetic Bead Screening Panel

96 well

Synonym(s):

Human screening panel, Luminex human screening panel, Millipore screening kit, Human screening kit, Luminex human screening immunoassay, Millipore screening panel, Multiplex screening kit, Multiplex screening panel

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

UNSPSC Code:
12161503
NACRES:
NA.84

Quality Level

100

species reactivity

human

manufacturer/tradename

Milliplex®

parameter

25 μL sample volume (per well)

assay range

intra-assay cv: ≤15
inter-assay cv: ≤20%
(≤25% for PDGF-AA)

technique(s)

multiplexing: suitable using : suitable

input

serum
cell culture supernatant
plasma

detection method

fluorometric (Luminex® xMAP®)

shipped in

wet ice

storage temp.

2-8°C

General description

The MILLIPLEX® PLEXpedition Screening Panel is a configurable multiplex immunoassay kit developed to simultaneously screen up to 115 targets including cytokines, chemokines, growth factors, matrix metalloproteinases (MMPs), and biomarkers of bone health, metabolism, and cardiovascular disease. Two Luminexlumi® instruments, the xMAP® INTELLIFLEX and the FLEXMAP 3D®, can analyze all 115 bead regions with comparable sensitivity and sample correlation while the MAGPIX® and Luminex 200™ instruments can detect specific subsets of 50 and 80 analytes, respectively. As a discovery biomarker tool this panel is provided in a matrix-free format to enable analyte detection in multiple sample types.


Research category : Bone, Cancer, Cardiovascular, Immune Response, Immunology, Metabolism/Endocrinology, Neuroscience, Toxicity

Specificity

There was no or negligible cross-reactivity between the antibodies for an analyte and any of the other analytes in this panel, with the following exceptions:
  • GIP and ENA-78 have low cross-reactivity with IL-23 (≤15%) and GRO (≤5%) recombinant proteins, respectively.
  • IL-12 (p40) has moderate, but expected, cross-reactivity with the recombinant proteins for IL-12 (p70) and IL-23 which both contain the p40 subunit.
  • MMP-3 may exhibit significant cross-reactivity with MMP-10 recombinant proteins due to high sequence homology, however, analysis demonstrated independent and differentiated measurement of MMP-3 and MMP-10 in biological samples.

Application

The MILLIPLEX® PLEXpedition Magnetic Bead Screening Panel is to be used for the simultaneous quantification of up to 115 analytes in your selected sample type. (NOTE: Instrument requirements vary based on analyte selection.) This is an overnight assay and requires 25 µL per well of neat or diluted sample. \
  • MAGPIX®/Luminex 200™/FLEXMAP 3D®/xMAP® INTELLIFLEX required for any or all of the following 50 analytes: EGF, FGF-2, Fractalkine, G-CSF, Ghrelin (Active), GIP, Glucagon, GM-CSF, Granzyme B, GROα, HGF, IFNα2, IFNγ, IL-10, IL-12 (p40), IL-12 (p70), IL-13, IL-15, IL-17A, IL-18, IL-1Ra, IL-1α, IL-1β, IL-2, IL-22, IL-23, IL-4, IL-5, IL-6, IL-7, IL-8, IP-10, Leptin, MCP-1, MIG, MIP-1α, MIP-1β, OPN, PDGF-AA, PDGF-BB, Perforin, RANTES, sCD40L, SCF, sFAS, sFASL, TGFα, TNFα, TRAIL, VEGF-A
  • Luminex 200™/FLEXMAP 3D®/xMAP® INTELLIFLEX required for any or all of the following 80 analytes: ACTH, BDNF, C-Peptide, EGF, Eotaxin, FABP4, FGF-2, FLT3 Ligand, Fractalkine, G-CSF, Ghrelin (Active), GIP, GLP-1 Total, Glucagon, GM-CSF, Granzyme A, Granzyme B, GROα, HGF, IFNα2, IFNγ, IL-10, IL-12 (p40), IL-12 (p70), IL-13, IL-15, IL-17A, IL-17F, IL-18, IL-1Ra, IL-1α, IL-1β, IL-2, IL-21, IL-22, IL-23, IL-3, IL-33, IL-4, IL-5, IL-6, IL-7, IL-8, IL-9, Insulin, IP-10, I-TAC, Leptin, MCP-1, MCP-3, M-CSF, MDC, MIG, MIP-1α, MIP-1β, MIP-3α, MMP-1, MMP-2, MMP-7, MMP-9, OPG, OPN, PDGF-AA, PDGF-BB, Perforin, PlGF, PP, PYY, RANTES, sCD40L, SCF, sFAS, sFASL, TARC, TGFα, TNFα, TNFβ, TRAIL, Troponin I, VEGF-A
  • FLEXMAP 3D®/xMAP® INTELLIFLEX required for any or all of the following 115 analytes: ACTH, Amylin (Active), BCA-1, BDNF, BNP, CK-MB, C-Peptide, DKK1, EGF, ENA-78, Eotaxin, Eotaxin-2, Eotaxin-3, Erythropoeitin (EPO), FABP3, FABP4, FGF-2, FGF-21, FGF-23, FLT3 Ligand, Fractalkine, G-CSF, Ghrelin (Active), GIP, GLP-1 Total, Glucagon, GM-CSF, GPC-2, Granzyme A, Granzyme B, GROα, HB-EGF, HGF, I-309, IFNα2, IFNγ, IL-10, IL-11, IL-12 (p40), IL-12 (p70), IL-13, IL-15, IL-17A, IL-17F, IL-18, IL-1Ra, IL-1α, IL-1β, IL-2, IL-21, IL-22, IL-23, IL-3, IL-33, IL-4, IL-5, IL-6, IL-7, IL-8, IL-9, Insulin, IP-10, I-TAC, Leptin, LIF, MCP-1, MCP-2, MCP-3, MCP-4, M-CSF, MDC, MIG, MIP-1α, MIP-1β, MIP-1Ϭ, MIP-3α, MIP-3β, MMP-1, MMP-10, MMP-12, MMP-2, MMP-3, MMP-7, MMP-9, Myostatin , NGF, NTproBNP, OPG, OPN, Osteocalcin, Osteonectin, PDGF-AA, PDGF-BB, Perforin, PlGF, PP, PYY, RANTES, sCD40L, SCF, SDF-1, sFAS, sFASL, SOST, TARC, TGFα, TNFα, TNFβ, TPO, TRAIL, Troponin I, TSLP, VEGF-A, VEGF-C, VEGF-D

Features and Benefits

This is a configurable kits. Design your multiplex kit by choosing available analytes within this panel based on your instrument.

Legal Information

FLEXMAP 3D system is a registered trademark of Luminex Corp
Luminex is a registered trademark of Luminex Corp
Luminex 200 system is a trademark of Luminex Corp
MAGPIX system is a registered trademark of Luminex Corp
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Sens. 1 - STOT RE 2

Target Organs

Respiratory Tract

Storage Class Code

10 - Combustible liquids

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service