719889
Resomer® RG 502, Poly(D,L-Lactide-co-Glycolide)
lactide:glycolide 50:50, ester terminated, Mw 7,000-17,000
Synonym(s):
PLGA
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About This Item
Linear Formula:
[C3H4O2]x[C2H2O2]y
UNSPSC Code:
12162002
NACRES:
NA.23
Recommended Products
form
amorphous
feed ratio
lactide:glycolide 50:50
mol wt
Mw 7,000-17,000
degradation timeframe
<3 months
viscosity
0.16-0.24 dL/g, 0.5 % (w/v) in chloroform(25 °C, Ubbelohde) (size 0c glass capillary viscometer)
transition temp
Tg 42-46 °C
shipped in
wet ice
storage temp.
2-8°C
Application
Resomer® RG 502 can be used to formulate a PLGA-based nano drug delivery system for the anti-inflammatory drug, 6-bromoindirubin-3′-glycerol-oxime ether (6BIGOE).
Itcan also be used to prepare control release formulations for Naloxone HCldelivery.
Itcan also be used to prepare control release formulations for Naloxone HCldelivery.
Features and Benefits
- Biocompatible
- Biodegradable
- Can be processed into almost any shape and size
- Tunable mechanical properties
Legal Information
Product of Evonik
RESOMER is a registered trademark of Evonik Rohm GmbH
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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Our purpose was to assess sustained delivery and enhanced efficacy of pirfenidone-loaded nanoparticles after intratracheal instillation.Poly(lactide-co-glycolide) nanoparticles containing pirfenidone (NPs) were prepared and characterized. Biodistribution of NPs and solution was assessed using LC-MS after intratracheal administration in C57Bl/6 mice at
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