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Merck

1659000

USP

Timerosal

United States Pharmacopeia (USP) Reference Standard

Sinónimos:

Etilmercuritiosalicilato de sodio, Mercuri-([o-carboxifenil]tio)etil sodium salt, Ácido 2-(etilmercuriomercapto)benzoico sodium salt, Ácido etilmercuritiosalicílico sodium salt

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About This Item

Fórmula lineal:
2-(C2H5HgS)C6H4CO2Na
Número de CAS:
Peso molecular:
404.81
Beilstein:
8169555
Número MDL:
Código UNSPSC:
41116107
ID de la sustancia en PubChem:
NACRES:
NA.24

grado

pharmaceutical primary standard

familia API

thimerosal

fabricante / nombre comercial

USP

mp

234-237 °C (dec.) (lit.)

aplicaciones

pharmaceutical (small molecule)

Formato

neat

temp. de almacenamiento

2-8°C

cadena SMILES

[Na+].CC[Hg]Sc1ccccc1C([O-])=O

InChI

1S/C7H6O2S.C2H5.Hg.Na/c8-7(9)5-3-1-2-4-6(5)10;1-2;;/h1-4,10H,(H,8,9);1H2,2H3;;/q;;2*+1/p-2

Clave InChI

RTKIYNMVFMVABJ-UHFFFAOYSA-L

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Descripción general

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Aplicación

Thimerosal USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Thimerosal Tincture
  • Thimerosal Topical Aerosol®
  • Thimerosal Topical Solution

Acciones bioquímicas o fisiológicas

El timerosal es un reactivo oxidante de sulfhidrilo (tiol) capaz de inhibir una amplia variedad de enzimas dependientes del sulfhidrilo y proteínas como la metionina sintasa dependiente de PI3-cinasa, receptores de transporte de glutamato y las ATPasas dependientes de Na++K+.

Nota de análisis

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Otras notas

Sales restrictions may apply.

Información legal

Aerosol is a registered trademark of Cytec Technology Corp.

Cláusula de descargo de responsabilidad

As part of the corporationglobal plan to support the Minamata Convention in eliminatingmercury-containing compounds, as of January 2021 customers will be required toprovide an End-Use Declaration. The sales of thimerosal will be restricted forapproved applications only, such as preservative in vaccine manufacturing,preservative in eye cosmetics, research use within academia (excludingpreservation intent) and as reference material only. The product is notintended for use as a biocide under global biocide regulations, including butnot limited to US EPA′s Federal Insecticide Fungicide and Rodenticide Act ,European Biocidal Products Regulation, Canada’s Pest Management RegulatoryAgency, Turkey’s Biocidal Products Regulation,Korea’s Consumer Chemical Products and Biocide Safety Management Act (K-BPR)and others.
For U.S. Customers: Contains mercury; Do not place in trash - dispose according to local, state, or federal laws.

Palabra de señalización

Danger

Clasificaciones de peligro

Acute Tox. 1 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - STOT RE 2 Oral

Órganos de actuación

Kidney

Código de clase de almacenamiento

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable


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Certificados de análisis (COA)

Lot/Batch Number

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Los clientes también vieron

Thimerosal Tincture
USP43-NF38: United States Pharmacopeia and National Formulary
United States Pharmacopeia, 4348-4348 (2013)
Thimerosal
USP43-NF38: United States Pharmacopeia and National Formulary
United States Pharmacopeia, 40(5), 4344-4344 (2020)
Thimerosal Topical Solution
USP43-NF38: United States Pharmacopeia and National Formulary
United States Pharmacopeia, 4347-4347 (2013)
Thimerosal Topical Aerosol
USP43-NF38: United States Pharmacopeia and National Formulary
United States Pharmacopeia, 4346-4346 (2018)
Xiaoling Li et al.
Toxicological sciences : an official journal of the Society of Toxicology, 139(2), 452-465 (2014-03-29)
Thimerosal is a vaccine antimicrobial preservative which has long been suspected an iatrogenic factor possibly contributing to neurodevelopmental disorders including autism. The association between infant vaccine thimerosal exposure and autism remains an open question. Although thimerosal has been removed from

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