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Merck
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Documentos clave

1478312

USP

Olanzapine Related Compound A

United States Pharmacopeia (USP) Reference Standard

Sinónimos:

5-Methyl-2-[(2-nitrophenyl)amino]-3-thiophenecarbonitrile

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About This Item

Fórmula empírica (notación de Hill):
C12H9N3O2S
Número de CAS:
138564-59-7
Peso molecular:
259.28
Beilstein/REAXYS Number:
7485862
MDL number:
MFCD06408054
UNSPSC Code:
41116107
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

olanzapine

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

[s]1c(c(cc1C)C#N)Nc2c(cccc2)[N+](=O)[O-]

InChI

1S/C12H9N3O2S/c1-8-6-9(7-13)12(18-8)14-10-4-2-3-5-11(10)15(16)17/h2-6,14H,1H3

InChI key

NPXUFPFFHANGDL-UHFFFAOYSA-N

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Olanzapine Related Compound A USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

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Referencia del producto
Descripción
Precios

1478301

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1478323

Olanzapine Related Compound B, United States Pharmacopeia (USP) Reference Standard

Y0001370

Olanzapine, European Pharmacopoeia (EP) Reference Standard

Y0001380

Olanzapine for system suitability, European Pharmacopoeia (EP) Reference Standard

Y0001392

Olanzapine impurity A, European Pharmacopoeia (EP) Reference Standard

1478334

Olanzapine Related Compound C, United States Pharmacopeia (USP) Reference Standard

PHR1825

Olanzapine, Pharmaceutical Secondary Standard; Certified Reference Material

BP1060

Olanzapine, British Pharmacopoeia (BP) Reference Standard

Y0002177

Olanzapine embonate for peak identification, CRS, European Pharmacopoeia (EP) Reference Standard

PHR2537

Olanzapine Related Compound B, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2538

Olanzapine Related Compound C, Pharmaceutical Secondary Standard; Certified Reference Material

pictograms

Environment
GHS09

signalword

Warning

hcodes

H410

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 1

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificados de análisis (COA)

Lot/Batch Number

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Christopher P Price et al.
Journal of the American Chemical Society, 127(15), 5512-5517 (2005-04-14)
The discovery and selective production of crystalline polymorphs, an outstanding problem in solid-state chemistry, is of great importance industrially in, for example, the manufacture of pharmaceuticals and pigments. Despite considerable efforts, no reliable method exists to produce all of the
K Adrjanowicz et al.
The Journal of chemical physics, 136(23), 234509-234509 (2012-07-12)
The organic liquid ROY, i.e., 5-methyl-2-[(2-nitrophenyl)amino]-3-thiophenecarbonitrile, has been a subject of detailed study in the last few years. One interest in ROY lies in its polymorph-dependent fast crystal growth mode below and above the glass transition temperature. This growth mode
Lian Yu
Accounts of chemical research, 43(9), 1257-1266 (2010-06-22)
Diamond and graphite are polymorphs of each other: they have the same composition but different structures and properties. Many other substances exhibit polymorphism: inorganic and organic, natural and manmade. Polymorphs are encountered in studies of crystallization, phase transition, materials synthesis
C A Mitchell et al.
Journal of the American Chemical Society, 123(44), 10830-10839 (2001-11-01)
Crystallization of 5-methyl-2-[(2-nitrophenyl)amino]-3-thiophenecarbonitrile (1), previously found to produce six conformational polymorphs from solution, on single-crystal pimelic acid (PA) substrates results in selective and oriented growth of the metastable "YN" (yellow needle) polymorph on the (101)(PA) faces of the substrate. Though
Ying Diao et al.
Journal of the American Chemical Society, 134(1), 673-684 (2011-12-06)
Although nanoporous materials have been explored for controlling crystallization of polymorphs in recent years, polymorphism in confined environments is still poorly understood, particularly from a kinetic perspective, and the role of the local structure of the substrate has largely been
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