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SMB00119

Sigma-Aldrich

Arjunolic acid

≥95% (LC/MS-ELSD)

Sinónimos:

2,3,23-Trihydroxyolean-12-en-28-oic acid

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About This Item

Fórmula empírica (notación de Hill):
C30H48O5
Número de CAS:
465-00-9
Peso molecular:
488.70
Número MDL:
MFCD11113458
Código UNSPSC:
12352205
ID de la sustancia en PubChem:
329824797
NACRES:
NA.25

Nivel de calidad

200

Ensayo

≥95% (LC/MS-ELSD)

Formulario

solid

aplicaciones

metabolomics
vitamins, nutraceuticals, and natural products

temp. de almacenamiento

−20°C

cadena SMILES

CC1(C)CC[C@@]2(CC[C@]3(C)C(=CC[C@@H]4[C@@]5(C)C[C@@H](O)[C@H](O)[C@@](C)(CO)[C@@H]5CC[C@@]34C)[C@@H]2C1)C(O)=O

InChI

1S/C30H48O5/c1-25(2)11-13-30(24(34)35)14-12-28(5)18(19(30)15-25)7-8-22-26(3)16-20(32)23(33)27(4,17-31)21(26)9-10-29(22,28)6/h7,19-23,31-33H,8-17H2,1-6H3,(H,34,35)/t19-,20+,21+,22+,23-,26-,27-,28+,29+,30-/m0/s1

Clave InChI

RWNHLTKFBKYDOJ-DDHMHSPCSA-N

Categorías relacionadas

Descripción general

Natural product derived from plant source.

Acciones bioquímicas o fisiológicas

Arjunolic acid (AA) is a triterpenoid saponin that has known anti-oxidant activity. AA has also shown promise in against type 1 diabetes through its prevention of hyperglycemia induced activation of MAPKs, PKC, NF-kB signaling cascades. Arjunolic acid is beneficial in protecting again acetaminophen (APAP)-induced liver and hepatocyte injury.

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

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Certificados de análisis (COA)

Lot/Batch Number
122228344V
122228133V
122228-133V

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Jyotirmoy Ghosh et al.
Biomaterials, 32(21), 4857-4866 (2011-04-14)
In spite of tremendous demand for the development and implementation of effective therapeutic strategies, limitations are still associated with doxorubicin-induced cardiotoxicity. Arjunolic acid (AA) has been shown to possess a multitude of biological functions. The purpose of the present study
Prasenjit Manna et al.
Chemico-biological interactions, 181(3), 297-308 (2009-08-18)
Diabetic nephropathy is a common cause for end-stage renal disease. Present study investigated the beneficial role of arjunolic acid (AA) against streptozotocin (STZ) induced diabetic nephropathy in rats. Diabetic renal injury was associated with increased kidney weight to body weight
Braja G Bag et al.
Langmuir : the ACS journal of surfaces and colloids, 25(15), 8663-8671 (2009-04-28)
Nine esters of a naturally occurring triterpenoid, arjunolic acid (from Terminalia arjuna), with alkyl chains have been synthesized, and their self-assembly has been studied in organic liquids. All of the esters examined were found to be excellent gelators. No birefringence
Prasenjit Manna et al.
Toxicology, 257(1-2), 53-63 (2009-01-10)
Increasing evidences in both experimental and clinical studies suggest that oxidative stress is involved in the pathogenesis of diabetic tissue damage. Pancreatic beta-cell death is the cause of decreased insulin production in diabetes. Streptozotocin (STZ) is widely used to induce
Rudiyansyah et al.
Journal of natural products, 69(8), 1218-1221 (2006-08-29)
Phytochemical exploration of a wood bark extract from Durio zibethinus afforded two new triterpenoids, namely, methyl 27-O-trans-caffeoylcylicodiscate (1) and methyl 27-O-cis-caffeoylcylicodiscate (2), a new phenolic, 1,2-diarylpropane-3-ol (3), and seven known compounds, fraxidin, eucryphin, boehmenan, threo-carolignan E, (-)-(3R,4S)-4-hydroxymellein, methyl protocatechuate, and
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