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Merck

S3875

Sigma-Aldrich

Seleno-DL-methionine

≥99% (TLC)

Sinónimos:

2-amino-4-(methylseleno)-Butanoic acid

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About This Item

Fórmula empírica (notación de Hill):
C5H11NO2Se
Número de CAS:
Peso molecular:
196.11
Beilstein/REAXYS Number:
1758204
EC Number:
MDL number:
UNSPSC Code:
12352209
PubChem Substance ID:
NACRES:
NA.26

product name

Seleno-DL-methionine, ≥99% (TLC)

Quality Level

assay

≥99% (TLC)

form

powder

color

white to off-white

application(s)

cell analysis

storage temp.

−20°C

SMILES string

C[Se]CCC(N)C(O)=O

InChI

1S/C5H11NO2Se/c1-9-3-2-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)

InChI key

RJFAYQIBOAGBLC-UHFFFAOYSA-N

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signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - STOT RE 2

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges


Certificados de análisis (COA)

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Susie Shih-Yin Huang et al.
Aquatic toxicology (Amsterdam, Netherlands), 126, 274-282 (2012-10-24)
Selenium (Se) and mercury (Hg) are prevalent pollutants of industrialized watersheds. However, when co-administered, Se has protective effects on organisms from Hg. The mechanism is not fully understood, but it is thought that Se reduces Hg availability, either by forming
Ian R Bothwell et al.
Journal of the American Chemical Society, 134(36), 14905-14912 (2012-08-25)
Posttranslational methylation by S-adenosyl-L-methionine(SAM)-dependent methyltransferases plays essential roles in modulating protein function in both normal and disease states. As such, there is a growing need to develop chemical reporters to examine the physiological and pathological roles of protein methyltransferases. Several
Stephanie A Schaefer et al.
Journal of molecular biology, 425(2), 222-231 (2012-11-20)
Sulfur, a key contributor to biological reactivity, is not amendable to investigations by biological NMR spectroscopy. To utilize selenium as a surrogate, we have developed a generally applicable (77)Se isotopic enrichment method for heterologous proteins expressed in Escherichia coli. We
Qun Liu et al.
Science (New York, N.Y.), 336(6084), 1033-1037 (2012-05-26)
Crystal structure analyses for biological macromolecules without known structural relatives entail solving the crystallographic phase problem. Typical de novo phase evaluations depend on incorporating heavier atoms than those found natively; most commonly, multi- or single-wavelength anomalous diffraction (MAD or SAD)
Pedro José Barbosa Pereira et al.
Journal of structural biology, 181(2), 89-94 (2012-11-28)
Selenomethionine labeling is the most common technique used in protein crystallography to derivatize recombinant proteins for experimental phasing using anomalous scattering at tunable synchrotron beamlines. Recently, it has been shown that UV radiation depletes electron density of selenium atoms of

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