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RAB0857

Sigma-Aldrich

Mouse Ptx3 / Pentraxin-related Protein PTX3 ELISA Kit

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About This Item

Código UNSPSC:
41116158
NACRES:
NA.32

reactividad de especies

mouse

envase

kit of 96 wells (12 strips x 8 wells)

técnicas

ELISA: suitable

entrada

sample type plasma
sample type serum
sample type cell culture supernatant(s)

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 0.6 ng/mL
standard curve range: 0.614-150 ng/mL

método de detección

colorimetric

Condiciones de envío

wet ice

temp. de almacenamiento

−20°C

Información sobre el gen

mouse ... Ptx3(19288)

Descripción general

The antibody pair provided in this kit recognizes mouse Pentraxin-related Protein PTX3 / Pentraxin 3.
The pentraxin3 (PTX3) gene encodes for a long PTX3 protein, an acute-phase protein. PTX3 protein is a member of the pentraxin family and is present in several cells and tissues. It is observed during brain inflammatory response and seizure. PTX3 plays a role in angiogenesis, tissue remodeling, and female fertility. It promotes phagocytosis of pathogen and inhibits the phagocytosis of apoptotic cells. The antibody pair provided in this kit recognizes mouse pentraxin-related protein PTX3 / pentraxin 3.

Aplicación

For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)

Los componentes del kit también están disponibles por separado

Referencia del producto
Descripción
SDS

  • RABTMB3ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)SDS

  • RABSTOP3ELISA Stop Solution (Item I)SDS

  • RABWASH420X Wash Buffer (Item B)SDS

Pictogramas

Corrosion

Palabra de señalización

Warning

Frases de peligro

Consejos de prudencia

Clasificaciones de peligro

Met. Corr. 1

Código de clase de almacenamiento

8A - Combustible corrosive hazardous materials

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable


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Jiale Diao et al.
Endocrine, 70(1), 78-84 (2020-04-18)
Transforming growth factor-β (TGF-β), recognized as a crucial factor in regulating fibrosis and tissue remodeling, plays a role in thyroid-associated ophthalmopathy (TAO). Pentraxin-3 (PTX3), a member of pentraxins, was recently implicated in many autoimmune and fibrotic diseases. Thus, we hypothesize
Hrishikesh S Kulkarni et al.
JCI insight, 5(17) (2020-08-05)
BACKGROUNDThe complement system plays a key role in host defense but is activated by ischemia/reperfusion injury (IRI). Primary graft dysfunction (PGD) is a form of acute lung injury occurring predominantly due to IRI, which worsens survival after lung transplantation (LTx).
Ning Xu et al.
Medicine, 99(3), e18740-e18740 (2020-02-06)
To investigate the interaction between the single nucleotide polymorphism of the 3' untranslated region (3'UTR) of the pentraxin 3 (PTX3) gene, as well as environmental factors and the preeclampsia risk in a Chinese Han population.Sanger sequencing was used to analyze
Hyejin Jeon et al.
Journal of neuroimmunology, 229(1-2), 63-72 (2010-08-03)
Microglia, as the phagocytes of the central nervous system, play an important role in the recognition, engulfment, and clearance of apoptotic cells and invading microbes. Proteins secreted from activated glial cells may affect microglial phagocytic activity. Secreted proteins of mixed
Beata Kusnierz-Cabala et al.
Clinical laboratory, 59(9-10), 1003-1008 (2013-11-28)
Pentraxin 3 (PTX3) belongs to the acute phase proteins; its concentration increases significantly in the early stages of inflammation. In nearly 20% of patients with acute pancreatitis (AP) escalated inflammation leads to the development of severe forms of the disease.

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